Results 261 to 270 of about 29,996 (293)

Decorin expression in quiescent myogenic cells

Biochemical and Biophysical Research Communications, 2008
Satellite cells are quiescent muscle stem cells that promote postnatal muscle growth and repair. When satellite cells are activated by myotrauma, they proliferate, migrate, differentiate, and ultimately fuse to existing myofibers. The remainder of these cells do not differentiate, but instead return to quiescence and remain in a quiescent state until ...
Takanori, Nishimura, Kenjiro, Nozu, Yasuhiro, Kishioka, Jun-Ichi, Wakamatsu, Akihito, Hattori   +4 more
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Affinity of Placental Decorin for Collagen

Bioscience, Biotechnology, and Biochemistry, 2000
Decorin was isolated from 7 M urea extract of bovine placental cotyledons by ion-exchange and hydrophobic chromatography. Decorin and its core protein showed a broad band at about 115 kDa and a single band at 47 kDa, respectively by SDS-PAGE. Anti-decorin core protein antiserum from pig skin was reacted with placental decorin and its core protein in ...
T, Batbayar, Y, Nomura, Y, Ishii, K, Shirai   +3 more
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Downregulation of Decorin and Transforming Growth Factor-β1 by Decorin Gene Suppression in Tendinocytes

Connective Tissue Research, 2005
Scars formed after tendonitis result in altered tissue mechanical properties after injury. The interaction of collagen molecules with decorin affects collagen fibrogenesis, and scar tissue is fragile as a consequence of a large amount of decorin in the scar.
Yoshinao, Hosaka, Rikio, Kirisawa, Naoki, Mafune, Kazushige, Takehana   +3 more
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Reconstruction of glycosaminoglycan chains in decorin

Biochemical and Biophysical Research Communications, 2002
The glycosaminoglycan chain of decorin from human spinal ligaments was digested using the hydrolysis of bovine testicular hyaluronidase. As a result, decorin with hexasaccharide, octasaccharide, and decasaccharide including the linkage region, GlcA-Gal-Gal-Xyl, was obtained.
Mito, Iwafune, Ikuko, Kakizaki, Masahiro, Yukawa, Daisuke, Kudo, Sakae, Ota, Masahiko, Endo, Keiichi, Takagaki   +6 more
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Decorin modulates matrix mineralization in vitro

Biochemical and Biophysical Research Communications, 2003
Decorin (DCN), a member of small leucine-rich proteoglycans, is known to modulate collagen fibrillogenesis. In order to investigate the potential roles of DCN in collagen matrix mineralization, several stable osteoblastic cell clones expressing higher (sense-DCN, S-DCN) and lower (antisense-DCN, As-DCN) levels of DCN were generated and the mineralized ...
Yoshiyuki, Mochida, Wagner R, Duarte, Hideki, Tanzawa, Eleftherios P, Paschalis, Mitsuo, Yamauchi   +4 more
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Differential interactions of decorin and decorin mutants with type I and type VI collagens

European Journal of Biochemistry, 2004
The small leucine‐rich proteoglycan decorin can bind via its core protein to different types of collagens such as type I and type VI. To test whether decorin can act as a bridging molecule between these collagens, the binding properties of wild‐type decorin, two full‐length decorin species with single amino acid substitutions (DCN E180K, DCN E180Q ...
Gordon, Nareyeck, Daniela G, Seidler, David, Troyer, Jürgen, Rauterberg, Hans, Kresse, Elke, Schönherr   +5 more
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Glomerular expression of biglycan and decorin and urinary levels of decorin in primary glomerular disease

Clinical Nephrology, 2004
Recent studies have suggested that small leucine-rich proteoglycans (SLRP) of the extracellular matrix play a major role in modulating the activity of growth factors and in regulating the deposition of collagens. In this study, the expression of the SLRPs biglycan and decorin in the glomeruli of patients with primary glomerular disease (minimal change ...
M, Kuroda, H, Sasamura, E, Kobayashi, R, Shimizu-Hirota, Y, Nakazato, M, Hayashi, T, Saruta   +6 more
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Structures of decorine and delcoridine

Chemistry of Natural Compounds, 1981
In order to confirm the structures of the alkaloids delcorine and delcoridine (O-demethyldelcorine) suggested previously, a direct passage has been performed from delcoridine to delcorine and from delcorine to delphatine. It has been shown that the α configuration of C1 - OCH3 previously suggested for delcorine and delcoridine is incorrect — it should ...
B. T. Salimov, M. G. Zhamierashvili, M. S. Yunusov   +2 more
openaire   +1 more source

Decorin-Mediated Effects in Cancer Cell Biology

Connective Tissue Research, 2008
Decorin is a multifunctional molecule of the extracellular matrix. Among the multitude of assigned functions the most intriguing is the ability to inhibit the growth and the metastasis of a wide range of cancer cells in vitro. Decorin was established to directly interact with EGFR and erb2, inducing protracted receptor internalization, which results in
Alexandros, Zafiropoulos, George N, Tzanakakis   +1 more
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Structural Change in Decorin with Skin Aging

Connective Tissue Research, 2006
Decorin, the main proteoglycan in skin, has a small size with a core protein of approximately 40kDa and one chondroitin sulfate/dermatan sulfate glycosaminoglycan (GAG) chain. The main function of decorin is to regulate the collagen matrix assembly. Decorin is distributed along collagen fibrils with the core protein and the decorin GAG chain controls ...
openaire   +2 more sources