Results 221 to 230 of about 85,945 (276)

Long non-coding RNAs and VEGF in ovarian cancer: mechanisms and therapeutic potential. [PDF]

J Ovarian Res
Abuarqoub AH, Abdulsahib WK, Jyothi SR, Nayak PP, Chauhan AS, Singla S, Sead FF, Zakirova N.   +7 more
europepmc   +1 more source

Combination Immunotherapy as a Promising Strategy to Overcome Immunotherapy Resistance: From Emergence to Next‐Generation Approaches

Advanced Science, EarlyView.
This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey, Sudhir Kumar Rai, Li Ma, Lauren Higa, Vedbar Khadka, Hua Yang, Youping Deng   +6 more
wiley   +1 more source

Phosphoglycerate dehydrogenase stabilizes protein kinase C delta type mRNA to promote hepatocellular carcinoma progression. [PDF]

Signal Transduct Target Ther
Cheng B, Peng P, Chen S, Liu R, Li X, Wang K, Ma J, Wang K, Tang N, Huang A.   +9 more
europepmc   +1 more source

Elevated TRIM25 Impairs Poly (ADP‐ribose) Metabolism via PARG Degradation and Mediates Compression‐Induced Intervertebral Disc Degeneration

Advanced Science, EarlyView.
TRIM25 acts as a multifunctional hub driving intervertebral disc degeneration under mechanical stress. Mechanical compression significantly upregulates TRIM25 expression, establishing it as a key E3 ubiquitin ligase platform. TRIM25 targets PARG and Ku80 via distinct molecular interfaces, triggering their ubiquitination and degradation.
Zhangrong Cheng, Haiyang Gao, Wenbo Wu, Pengzhi Shi, Xianglong Chen, Zimu Yu, Wang Wu, Kangcheng Zhao, Cao Yang, Yukun Zhang   +9 more
wiley   +1 more source

Alternative Splicing-Mediated Resistance to Antibody-Based Therapies: Mechanisms and Emerging Therapeutic Strategies. [PDF]

Int J Mol Sci
Choi S, Kang J, Kim JH.
europepmc   +1 more source

Noise Fingerprints as a Quantitative Order Parameter for Polarization‐ and Defect‐Mediated Switching in Hafnia Ferroelectrics

Advanced Science, EarlyView.
Low‐frequency noise fingerprints in hafnia ferroelectrics provide a quantitative handle to resolve the long‐standing debate between polarization‐mediated and defect‐mediated switching. By tuning oxygen vacancy density via ALD O3 dose time and applying a physically constrained deconvolution, we extract bias‐resolved current fractions for both mechanisms
Ryun‐Han Koo, Jiseong Im, Joon Hwang, Sung‐Ho Park, Jonghyun Ko, Kangwook Choi, Sangwoo Ryu, Gyuweon Jung, Jong‐Ho Lee   +8 more
wiley   +1 more source

Asymmetric Protocols for Mode Pairing Quantum Key Distribution with Finite-Key Analysis. [PDF]

Entropy (Basel)
Li Z, Dou T, Xie Y, Kong W, Liu Y, Ma H, Tang J.   +6 more
europepmc   +1 more source

Disrupting α-Synuclein-ClpP interaction restores mitochondrial function and attenuates neuropathology in Parkinson's disease models. [PDF]

Mol Neurodegener
Hu D, Sun X, Qi X.
europepmc   +1 more source

Thirty Years of Mentoring by "Bob Chan" of Young Japanese Surgeons to Become Scientists: An Adventure of Love. [PDF]

Ann Gastroenterol Surg
Hoffman RM, Miyake K, Endo I.
europepmc   +1 more source

Detection of alternative splicing: deep sequencing or deep learning? [PDF]

Brief Bioinform
Hackl LM, Neuhaus F, Ameling S, Völker U, Baumbach J, Tsoy O.   +5 more
europepmc   +1 more source