Results 61 to 70 of about 328,079 (346)

Differential modulation of excitatory and inhibitory neurons during periodic stimulation [PDF]

, 2016
Non-invasive transcranial neuronal stimulation, in addition to deep brain stimulation, is seen as a promising therapeutic and diagnostic approach for an increasing number of neurological diseases such as epilepsy, cluster headaches, depression, specific ...
Alarcón, Ali, Alon, Anderson, Antal, Antal, Berényi, Birdno, Boon, Boëx, Breakspear, Brumberg, Bullmore, Börgers, Chou, Coenen, Concerto, Connors, Cook, Davis, Dayan, de Hemptinne, Deans, Destexhe, Eichler, Eickenscheidt, Fisher, Fisher, Freeman, Freeman, Fröhlich, Gall, Ghezzi, Gironell, Grassi, Green, Grover, Guillamon, Henn, Herrmann, Herz, Hodaj, Hodgkin, Islam, Izhikevich, Jiménez-Ponce, Jorge, Joucla, Kanai, Kohl, Krack, Krause, Lettieri, Lewis, Liew, Liu, Loddenkemper, Lozano, Lozano, Lu, Mainen, Matharu, McConnell, McIntyre, McIntyre, McIntyre, Miller, Miocinovic, Moliadze, Mufti Mahmud, Nelson, Nowak, Nuttin, Obeso, Orosz, Paulus, Piacentino, Press, Radman, Reato, Rizvi, Rizzo, Roth, Rotstein, Salanova, Shin, Sillay, Stefano Vassanelli, Sun, Traub, Vassanelli, Vassanelli, Volkmann, Wang, Watts, Zaehle   +95 more
core   +3 more sources

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Desynchronizing effect of high-frequency stimulation in a generic cortical network model

, 2012
Transcranial Electrical Stimulation (TCES) and Deep Brain Stimulation (DBS) are two different applications of electrical current to the brain used in different areas of medicine. Both have a similar frequency dependence of their efficiency, with the most
A Antal, A Antal, A Benabid, A Compte, A Gupta, A Limoge, A Limoge, A Sances Jr, AS Pikovsky, B Nuttin, C Börgers, CC McIntyre, E Schöll, EM Izhikevich, EM Izhikevich, EM Izhikevich, EM Izhikevich, F Velasco, H Markram, J Lian, J Yianni, JA Acebrón, JA Obesó, JD Geyer, Jens Christian Claussen, JL Houeto, KJ Ressler, L Gang, L Garcia, M Steriade, Markus Schütt, P Coubes, R Kumar, R Wang, SC Bellinger, TR Anderson, V Visser-Vandewalle, X Zhang, Y Liu, Y Su   +39 more
core   +1 more source

Neurosurgery for psychopaths? The problems of empathy and neurodiversity [PDF]

, 2016
I argue that deep brain stimulation (DBS) is a bad approach for incarcerated psychopaths for two reasons. First, given what we know about psychopathy, empathy, and DBS, it is unlikely to function as an effective treatment for the moral problems that ...
Ramirez, Erick
core   +1 more source

About deep brain stimulation [PDF]

Neurology, 2015
Deep brain stimulation (DBS) is a surgery that is used to treat a number of disabling symptoms of neurologic diseases. These include symptoms of Parkinson disease (PD), essential tremor, dystonia, or obsessive-compulsive disorder. It has also been used in Tourette syndrome, neuropathic pain, and depression. A report of the first successful clinical use
João, Massano, Alexander I, Tröster
openaire   +2 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

2008 Progress Report on Brain Research [PDF]

, 2008
Highlights new research on various disorders, nervous system injuries, neuroethics, neuroimmunology, pain, sense and body function, stem cells and neurogenesis, and thought and memory.
Eve Marder, Mahlon R. DeLong, Michael S. Gazzaniga, Thomas Wichmann   +3 more
core  

Directional Deep Brain Stimulation [PDF]

Neurotherapeutics, 2019
Over the last years, deep brain stimulation has seen many technological innovations. New electrode designs allowing to direct the current flow not only in the vertical but also in the horizontal plane are the most recent. We summarize the concept of "directional deep brain stimulation" with its opportunities and challenges and the available study data ...
Frank Steigerwald, Cordula Matthies, Jens Volkmann   +2 more
openaire   +2 more sources

Transcriptional regulation of neuropeptide receptors underlies context‐dependent adaptation in Drosophila melanogaster

FEBS Open Bio, EarlyView.
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu, Yanan Wei, Zekun Wu, Tianmu Zhang, DoHoon Lee, Hadi Najafi, Woo Jae Kim   +6 more
wiley   +1 more source

In Parkinson’s disease dopaminergic medication and deep brain stimulation of the subthalamic nucleus increase motor, but not reflection and cognitive impulsivity

Frontiers in Neuroscience
BackgroundParkinson’s disease is associated with increased impulsivity, which can be divided into several domains: motor (consisting of proactive and reactive subdomains), reflection, and cognitive impulsivity.
Martijn Hendriks, Martijn Hendriks, Saman Vinke, Rok Berlot, Rok Berlot, Mitja Benedičič, Marjan Jahansahi, Maja Trošt, Maja Trošt, Dejan Georgiev, Dejan Georgiev   +10 more
doaj   +1 more source