Results 61 to 70 of about 315,574 (256)

Computational analysis of transcranial magnetic stimulation in the presence of deep brain stimulation probes

open access: yesAIP Advances, 2017
Transcranial Magnetic Stimulation is an emerging non-invasive treatment for depression, Parkinson’s disease, and a variety of other neurological disorders. Many Parkinson’s patients receive the treatment known as Deep Brain Stimulation, but often require
F. Syeda   +3 more
doaj   +1 more source

Sex modulates the outcome of subthalamic nucleus deep brain stimulation in patients with Parkinson’s disease

open access: yesNeural Regeneration Research, 2023
There are many documented sex differences in the clinical course, symptom expression profile, and treatment response of Parkinson’s disease, creating additional challenges for patient management.
Tian-Shuo Yuan   +7 more
doaj   +1 more source

Human Sensation of Transcranial Electric Stimulation. [PDF]

open access: yes, 2019
Noninvasive transcranial electric stimulation is increasingly being used as an advantageous therapy alternative that may activate deep tissues while avoiding drug side-effects. However, not only is there limited evidence for activation of deep tissues by
Richardson, Matthew   +4 more
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

In Parkinson’s disease dopaminergic medication and deep brain stimulation of the subthalamic nucleus increase motor, but not reflection and cognitive impulsivity

open access: yesFrontiers in Neuroscience
BackgroundParkinson’s disease is associated with increased impulsivity, which can be divided into several domains: motor (consisting of proactive and reactive subdomains), reflection, and cognitive impulsivity.
Martijn Hendriks   +10 more
doaj   +1 more source

Numerical characterization of intraoperative and chronic electrodes in deep brain stimulation [PDF]

open access: yes, 2015
An intraoperative electrode (microelectrode) is used in the deep bra In stImulation (DBS) technique to pinpoint the brain target and to choose the best parameters for the electrical stimulus.
Apollonio, Francesca   +4 more
core   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Vestibular Evoked Myogenic Potentials (VEMPs) in Parkinson’s Disease Patients with Monopolar Deep Brain Stimulation

open access: yesSignals
Whilst balance disturbances are common in people with advanced Parkinson’s disease, it has not previously been possible to record vestibular evoked myogenic potentials (VEMPs), and thus otolithic function, during monopolar deep brain stimulation (DBS ...
Kim E. Hawkins   +5 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Neuronal Activity in the Human Subthalamic Nucleus Encodes Decision Conflict during Action Selection [PDF]

open access: yes, 2012
The subthalamic nucleus (STN), which receives excitatory inputs from the cortex and has direct connections with the inhibitory pathways\ud of the basal ganglia, is well positioned to efficiently mediate action selection.
Baltuch, G. H.   +5 more
core   +2 more sources

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