Completing the puzzle: why studies in non-human primates are needed to better understand the effects of non-invasive brain stimulation [PDF]
Brain stimulation is a core method in neuroscience. Numerous non-invasive brain stimulation (NIBS) techniques are currently in use in basic and clinical research, and recent advances promise the ability to non-invasively access deep brain structures. While encouraging, there is a surprising gap in our understanding of precisely how NIBS perturbs neural
arxiv
A unified connectomic target for deep brain stimulation in obsessive-compulsive disorder
Multiple surgical targets for treating obsessive-compulsive disorder with deep brain stimulation (DBS) have been proposed. However, different targets may modulate the same neural network responsible for clinical improvement.
Ningfei Li+18 more
semanticscholar +1 more source
Deep brain stimulation modulates synchrony within spatially and spectrally distinct resting state networks in Parkinson's disease [PDF]
Oswal et al. characterise the effect of deep brain stimulation (DBS) on STN-cortical synchronisation in Parkinson-s disease. They propose that cortical driving of the STN in beta frequencies is subdivided anatomically and spectrally, corresponding to the
Beudel, Martijn+7 more
core +3 more sources
Multi-Disease Deep Brain Stimulation
Current closed-loop deep brain stimulation (DBS) devices can generally tackle one disorder. This paper presents the design and evaluation of a multi-disease closed-loop DBS device that can sense multiple brain biomarkers, detect a disorder, and ...
Mahboubeh Parastarfeizabadi+2 more
doaj +1 more source
Preliminary Guidelines for Electrode Positioning in Noninvasive Deep Brain Stimulation via Temporally Interfering Electric Fields [PDF]
Advancements in neurosurgical robotics have improved medical procedures, particularly deep brain stimulation, where robots combine human and machine intelligence to precisely implant electrodes in the brain. While effective, this procedure carries risks and side effects.
arxiv
Brain Modeling for Control: A Review [PDF]
Neurostimulation technologies have seen a recent surge in interest from the neuroscience and controls communities alike due to their proven potential to treat conditions such as Parkinson's Disease, and depression. The provided stimulation can be of different types, such as electric, and optogenetic, and is generally applied to a specific region of the
arxiv +1 more source
There are many documented sex differences in the clinical course, symptom expression profile, and treatment response of Parkinson’s disease, creating additional challenges for patient management.
Tian-Shuo Yuan+7 more
doaj +1 more source
Neural Fiber Activation in Unipolar vs Bipolar Deep Brain Stimulation [PDF]
Deep Brain Stimulation (DBS) is an established and powerful treatment method in various neurological disorders. It involves chronically delivering electrical pulses to a certain stimulation target in the brain in order to alleviate the symptoms of a disease.
arxiv
Informed consent decision-making in deep brain stimulation [PDF]
Deep brain stimulation (DBS) has proved useful for several movement disorders (Parkinson’s disease, essential tremor, dystonia), in which first and/or second line pharmacological treatments were inefficacious.
Appelbaum+6 more
core +2 more sources
Debugging Adaptive Deep Brain Stimulation for Parkinson's Disease
Deep brain stimulation (DBS) is a successful treatment for patients with Parkinson's disease. In adaptive DBS, stimulation is titrated according to feedback about clinical state and underlying pathophysiology. This contrasts with conventional stimulation,
S. Little, P. Brown
semanticscholar +1 more source