Results 61 to 70 of about 4,101,096 (348)

Using web-based peer assessment in fostering deep learning in computer programming [PDF]

open access: yes, 2004
Active learning is considered by many academics as an important and effective learning strategy. Students can improve the quality of their work by developing their higher cognitive skills through reflection on their own ideas and practice of analytic and
Sitthiworachart, Jirarat, Joy, Mike
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Tailoring Thermal Energy Supply Towards the Advanced Control of Deformation Mechanisms in 3D Forming of Paper and Board

open access: yesJournal of Manufacturing and Materials Processing
The temperature of the tools and the moisture content of the material play a significant role in the 3D forming of paperboard in terms of the degree of forming and the quality of the formed part.
Leonard Vogt, Marek Hauptmann
doaj   +1 more source

Ear height control by die radius shape in cylindrical deep drawing [PDF]

open access: yesMATEC Web of Conferences
This study presents the relationship between die radius shape and anisotropy that suppresses ear height in cylindrical deep drawing. In deep drawing, the cup is formed with irregularities on the edge, called “earing”, due to the anisotropy of sheet ...
Muraoka Tsuyoshi   +3 more
doaj   +1 more source

Deep Drawing of AISI 304 Blanks with Polymer Punches Produced by Additive Manufacturing: Effects of Process Scalability

open access: yesApplied Sciences, 2022
Rapid tooling is a methodology which aims to integrate additive manufacturing into the production of tools to be used in casting, forming or machining processes.
Luca Giorleo
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Effect of lubricant type on deep drawing ratio and drawing force during cylindrical cup deep drawing

open access: yes, 2022
Cylindrical cup deep drawing technology is used in various manufacturing processes. For example, it is used in the automotive industry to manufacture auto parts. It is also used in the manufacture of household items. Lubricants are used in metal forming,
shewakh, walid M
core  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

STRENGTHENING TREATMENT OF DEEP-DRAWING DIES

open access: yesНаука и техника, 2010
The paper investigates a possibility to increase resistance of die tool for deep-drawing while applying surface strengthening with the help of diffusion carbidized coatings.
N. A. Galynskaya   +3 more
doaj  

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