Results 61 to 70 of about 3,533,822 (252)

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

Influence of alternating bending on springback behavior of parts in deep drawing process with macro-structured tools

open access: yesMATEC Web of Conferences, 2018
In today’s industry, waste prevention and an efficient use of resources are becoming more important due to economic and environmental requirements. Especially in forming processes such as deep drawing, a reduced use of lubricants is highly promising for ...
Mousavi Ali   +2 more
doaj   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

FEM SIMULATION OF DEEP DRAWING PROCESS OF ALUMINIUM ALLOYS [PDF]

open access: yesApplied Computer Science, 2015
This paper presents results of research with FEM simulation of sheet metal forming process. The two types of aluminium alloys from 5XXX and 6XXX series, which are used in automotive industry, were compared.
Jan SLOTA   +4 more
doaj  

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

open access: yesFEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo   +4 more
wiley   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Damage Evolution in Nakajima Tests of DP800 Dual Phase Steel

open access: yes, 2022
Art. 012048, 7 S.In order to extend the understanding of damage evolution in sheet metal forming, standardized Nakajima tests are carried out on a DP800 dual phase steel. Sample geometries for characteristic stress-strain states are drawn in incrementing
Klocke, Fritz   +3 more
core   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

open access: yesFEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez   +6 more
wiley   +1 more source

Study on micro extra deep drawing process with ultrahigh fluid pressure and press motion controls

open access: yesMATEC Web of Conferences, 2015
A novel micro extra deep drawing process with ultrahigh fluid pressure and press motion controls are developed. A space between the blank and 1st punch is made by the press motion at the 2nd drawing stage and the ultrahigh pressure is applied so as to be
Sato Hideki   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy