Results 101 to 110 of about 1,292,419 (308)
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Report of epibiont Thecacineta calix (Ciliophora: Suctorea) on deep sea Desmodora (Nematoda) from the Andaman Sea, Indian Ocean [PDF]
, 2009 Suctorian epibionts Thecacineta calix attached on the cuticle of nematodes Desmodora sphaerica and D. pontica are reported here from the deep sea hexactinellid sponge Pheronema sp. from the Andaman Sea (Indian Ocean). The epibiont T.
Baban, Іngole +4 more
core +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Body force-based method for determining flow velocity of sea water artesian circulating system
Zhongguo Jianchuan Yanjiu, 2019 [Objectives]Establish a method capable of quickly calculating the flow velocity of an artesian circulating system,in order to optimize and compare multiple design schemes for key components of the sea water artesian circulating system.[Methods]Numerical ...
Chen Kang +3 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Natural Product Reports, 2008 This review covers the 390 novel marine natural products described to date from deep-water (>50 m) marine fauna, with details on the source organism, its depth and country of origin, along with any reported biological activity of the metabolites. Relevant synthetic studies on the deep-sea natural products have also been included.
openaire +4 more sources
Deep pockets for deep seas [PDF]
Eos, Transactions American Geophysical Union, 1999 Peter Auster, a fisheries ecologist with the National Undersea Research Center in Connecticut, plans to assess degradation of the deep‐shelf seafloor from bottom trawling. Magnus Ngoile, an official with Tanzania's National Environmental Management Council, will work on building capacity of poor villagers to protect their coastline.
openaire +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Deep sea in deep trouble? [PDF]
Current Biology, 2015 Ahead of the imminent start of the industrial exploitation of deep sea resources, an EU report finds that scientific knowledge and understanding of this environment and its ecosystems still fall short of what would be needed for a sustainable use.
openaire +2 more sources