Results 111 to 120 of about 204,461 (310)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Post-larval development in deep-sea echinoderms
, 1998 The post-larval phase is an essential period in the life history of marine invertebrates; vulnerable to high mortality, it ultimately influences the distribution and abundance of adult populations.
Sumida, P.Y.G.
core
The deep-sea macrobenthos on the continental slope of the northwestern Mediterranean Sea: a quantitative approach [PDF]
, 1999 As part of the ECOMARGE operation (J.G.O.F.S. France), macrobenthic assemblages in the Toulon Canyon were described and quantified on the basis of sampling carried out between 250 and 2000 m depth on the Mediterranean continental slope. Results show that
Le Campion, Joel +7 more
core +1 more source
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Viral ecogenomics across oxic and anoxic zones of the Yongle Blue Hole
Environmental MicrobiomeBackground Deep ocean blue holes are characterized by distinct physicochemical gradients and complex biological processes, and Yongle Blue Hole (YBH) in the South China Sea (SCS) is the world’s deepest (301 m) underwater cavern with unique environmental ...
Ming Yang +6 more
doaj +1 more source
水下无人系统学报To address the problems of refined perception and discrimination of sound features caused by complex marine soundscapes and the variable characteristics of underwater target signals, this paper proposed a marine sound separation algorithm based on time ...
Yudi WANG, Mingzhong YANG, Lixin LIU
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
, 1989 Drilling results and seismic-reflection records at and across Ocean Drilling Program (ODP) Sites 645 (western Baffin Bay), 646, and 647 (Labrador Sea) provide important constraints on the history of deep-water circulation and sedimentation in response to
Srivastava, S.P. +9 more
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source