Results 61 to 70 of about 798,589 (237)

Division of Magnetic Flux Rope via Magnetic Reconnection Observed in the Magnetotail

Geophysical Research Letters, 2023
Using high‐resolution data from Magnetospheric Multiscale (MMS) mission, we report an intense current layer at the center of a flux rope (FR) in the magnetotail.
Xinmin Li, Rongsheng Wang, Quanming Lu
doaj   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

The Deep Space Network: A Radio Communications Instrument for Deep Space Exploration [PDF]

The primary purpose of the Deep Space Network (DSN) is to serve as a communications instrument for deep space exploration, providing communications between the spacecraft and the ground facilities.
Armstrong, J. W., Burow, N. A., Donnelly, H., Kinman, P. W., Noreen, G. K., Petty, S. M., Renzetti, N. A., Slobin, S. D., Stelzried, C. T., Trowbridge, D. L.   +9 more
core   +1 more source

A DEEP SPACE HABITAT FOR EXPLORATION [PDF]

, 2012
The paper describes a habitable module to be used for long duration space exploration missions. The Deep Space Habitat (DSH) is conceived as a cis-lunar orbital infrastructure and a space-ship for deep space exploration missions.
Gargioli, E., Lorenzoni, A., Viscio, Maria Antonietta   +2 more
core  

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Trade studies for nuclear space power systems [PDF]

As human visions of space applications expand and as we probe further out into the universe, our needs for power will also expand, and missions will evolve which are enabled by nuclear power.
Bents, David J., Bloomfield, Harvey S., Smith, John M.   +2 more
core   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Formation of Lunar Swirls: Implication from Derived Nanophase Iron Abundance

Remote Sensing
Lunar swirls are enigmatic features on the Moon’s surface, and their formation remains debated. Previous studies suggest that the distinctive spectral characteristics of lunar swirls result from the asymmetric space weathering between their bright ...
Wanqi Zhao, Xin Ren, Bin Liu, Yao Xiao, Dawei Liu   +4 more
doaj   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Hands-Free Control Interfaces for an Extra Vehicular Jetpack [PDF]

, 2012
The National Aeronautics and Space Administration (NASA) strategic vision includes, as part of its long-term goals, the exploration of deep space and Near Earth Asteroids (NEA).
Curiel, Pedro H., Schreiner, Sam, Zumbado, Jennifer Rochlis   +2 more
core   +1 more source