Results 61 to 70 of about 2,478,930 (305)
Development of a 140 MPa Deep In Situ Pressure-Preserved Coring Controller
Applied SciencesDeep in situ pressure coring provides an accurate means of determining oil and gas reserve parameters. The key to achieving pressure coring at depths exceeding 5000 m lies in the ultimate bearing strength and stability of the pressure controllers. Due to
Cong Li +5 more
doaj +1 more source
European Journal of Taxonomy, 2020 This study reports on 25 species of hydroids occurring in the collections gathered during KANACONO and KANADEEP expeditions carried out in the SE of New Caledonia in 2016, and off the western coast of the island in 2017, respectively.
Horia R. Galea, Davide Maggioni
doaj +1 more source
A deep-sea coral record of North Atlantic radiocarbon through the Younger Dryas: Evidence for intermediate water/deepwater reorganization [PDF]
, 2006 Our record of Younger Dryas intermediate-depth seawater Δ^(14)C from North Atlantic deep-sea corals supports a link between abrupt climate change and intermediate ocean variability.
Adkins, Jess F. +4 more
core +2 more sources
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
MachinesThe reciprocating plate column is a kind of column with the plates driven by a geared motor, and it has advantages in regard to efficiency compared to traditional columns in the extraction process, however, it comes with an increase in energy consumption.
Kai Guo +6 more
doaj +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Open Geosciences, 2018 The architecture and quality of lacustrine turbidites that act as petroleum reservoirs are less well documented. Reservoir architecture and multiscale heterogeneity in turbidites represent serious challenges to production performance.
Munawar Muhammad Jawad +8 more
doaj +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Steep sharp-crested gravity waves on deep water
, 2001 A new type of steady steep two-dimensional irrotational symmetric periodic gravity waves on inviscid incompressible fluid of infinite depth is revealed.
A. I. Nekrasov +16 more
core +1 more source