Results 91 to 100 of about 7,638,076 (261)

Serum cystatin C levels are independently correlated with cognitive impairment in individuals with cerebral small vessel disease

Frontiers in Neuroscience
Background and purposePrevious studies have shown that serum cystatin C (CysC) is associated with cerebral small vessel disease (CSVD) and that elevated CysC levels are linked to an increased risk of cognitive impairment in the elderly.
Danheng Mo, Danheng Mo, Mingchun Li, Xihua Guo, Lu Zhou, Jianwen Yang, Tao Lei, Wenping Zou, Qiang Lei, Qing Wang, Chunguang Li, Xi Tao, Xi Tao   +12 more
doaj   +1 more source

White matter abnormalities in autism.

, 2013
Two children illustrating the principal categories of white matter signal abnormalities. Figure 1A. Punctate T2 Hyperintensity: Abnormal findings were placed in this category when small (
Isabelle Meresse (374665), Nadia Bahi-Buisson (374561), Nathalie Boddaert (374656), Yves Samson (143766), Francis Brunelle (374668), Isabelle Desguerre (374614), Laurence Laurier (374667), Nadia Chabane (374670), David Seidenwurm (374663), Arnold Munnich (115628), Marie-Christine Mouren (184946), Mônica Zilbovicius (374657), Marie Bourgeois (374661), Anne Philipe (374658), Laurence Robel (374660), Catherine Barthélemy (5653867)   +15 more
core   +1 more source

9.4‐Tesla magnetic resonance imaging in focal epilepsy patients with high‐resolution surface‐based profiling of focal cortical dysplasias

Epilepsia, EarlyView.
Abstract Objective The detection of subtle epileptogenic lesions such as focal cortical dysplasias (FCDs) is a clinical challenge in the management of drug‐resistant focal epilepsy (DRFE). Ultra‐high‐field (UHF) magnetic resonance imaging (MRI) offers increased signal‐to‐noise ratios and spatial resolution compared to 3‐T MRI and may improve diagnostic
Cornelius Kronlage, Pascal Martin, Benjamin Bender, Gisela E. Hagberg, Jonas Bause, Joana R. A. Loureiro, Mathilde Ripart, Sophie Adler, Konrad Wagstyl, Holger Lerche, Niels K. N. Focke, Esther Kuehn   +11 more
wiley   +1 more source

Quantifying White Matter Hyperintensities: Automated Volumetry Compared with Visual Grading Scales

Medicina
Background and objectives. White matter hyperintensities (WMHs) on brain magnetic resonance imaging (MRI) are linked to cognitive decline, but clinical assessment still relies mainly on visual grading (Fazekas), which is coarse and rater-dependent.
Arturs Titovs, Artūrs Šilovs, Kalvis Kaļva, Ardis Platkājis, Andrejs Kostiks, Kristīne Šneidere, Guntis Karelis, Ainārs Stepens, Nauris Zdanovskis   +8 more
doaj   +1 more source

Repetitive clustered low‐voltage fast activity on intracranial electroencephalogram in mild malformation of cortical development with oligodendroglial hyperplasia and epilepsy: A candidate electroencephalographic biomarker study

Epilepsia, EarlyView.
Abstract Objective Mild malformation of cortical development with oligodendroglial hyperplasia and epilepsy (MOGHE) is a recently recognized cause of drug‐resistant focal epilepsy. It is often magnetic resonance imaging‐negative or radiologically resembles focal cortical dysplasias, which makes recognition difficult and limits presurgical counseling ...
Vadym Gnatkovsky, Ekaterina Poguzhelskaya, Valeri Borger, Tobias Baumgartner, Rainer Surges, Kerstin Alexandra Klotz, Valentina Zschernack, Till Hartlieb, Manfred Kudernatsch, Ahmed Gaballa, Thomas Cloppenborg, Friedrich G. Woermann, Thilo Kalbhenn, Hajo Hamer, Stephanie Gollwitzer, Stefan Rampp, Daniel Delev, Florian Mayer, Karl Rössler, Valerie Anne Quinot, Angelika Mühlebner, Rafael Toledano, Antonio Gil‐Nagel, Roland Coras, Ingmar Blümcke, Katja Kobow   +25 more
wiley   +1 more source

Research progress on the use of the optical coherence tomography system for the diagnosis and treatment of central nervous system tumors

Ibrain, Volume 11, Issue 1, Page 3-18, Spring 2025.
With the advantages of high‐resolution imaging, efficient image acquisition, intraoperative real‐time detection, and radiation‐free and noninvasive characteristics, optical coherence tomography (OCT) provides accurate diagnosis and effective intraoperative guidance for the minimally invasive diagnosis and treatment of central nervous system (CNS ...
Jiuhong Li, Ziba Ayi, Gonggong Lu, Haibo Rao, Feilong Yang, Jing Li, Jiachen Sun, Junlin Lu, Xulin Hu, Si Zhang, Xuhui Hui   +10 more
wiley   +1 more source

Larger deep white matter hyperintensity volume correlates with more severe social behavioral changes in patients with subacute ischemic stroke. [PDF]

Front Aging Neurosci, 2023
Qu JF, Hu HH, Liu JF, Zhou YQ, Cheng WY, Shi L, Luo YS, Zhao L, Chen YK.   +8 more
europepmc   +1 more source

Functional Imaging for Identification of Functionally Critical Brain Regions to Spare in Glioma Radiation Therapy Planning: A Systematic Review

Journal of Medical Radiation Sciences, EarlyView.
This review highlights the role of functional imaging in sparing cognitive brain regions during glioma radiotherapy. It shows promising dose reduction without compromising target coverage, but evidence remains limited, requiring standardisation and prospective validation.
Li Wen Yeo, John T. Ryan
wiley   +1 more source

Dominant ELOVL1‐Related Ichthyotic Keratoderma (IKSHD) in an Adult: Preserved Cognition With Functional Autonomy and Epilepsy

JEADV Clinical Practice, EarlyView.
ABSTRACT Ichthyotic keratoderma with spasticity, hypomyelination and dysmorphic features (IKSHD; OMIM #618527) is an ultra‐rare neuroichthyosis caused by dominant variants in ELOVL1, the elongase of very‐long‐chain fatty acids required for both the epidermal permeability barrier and central nervous system myelin.
Roxana Pirker, Lea Pock, Friedrich Breier, Christian Posch   +3 more
wiley   +1 more source

Heme Oxygenase‐1 Gene (GT)n Polymorphism Linked to Deep White Matter Hyperintensities, Not Periventricular Hyperintensities

Journal of the American Heart Association
Background Oxidative stress plays a principal role in the pathogenesis of white matter hyperintensities (WMHs). The induction of heme oxygenase‐1 ( HO‐1 ) gene in the brain represents 1 of the pivotal mechanisms to counteract the noxious effects of reactive oxygen species, and the ...
Junting Chen, Jinrui Li, Xiaomian Wang, Xiaoli Fu, Jianxia Ke, Jintao Li, Jia Wen, Kailin Cheng, Shuen Li, Zhu Shi   +9 more
openaire   +3 more sources