Results 71 to 80 of about 7,638,076 (261)

Skip Connection U-Net for White Matter Hyperintensities Segmentation From MRI

IEEE Access, 2019
White matter hyperintensity (WMH) is associated with various aging and neurodegenerative diseases. In this paper, we proposed and validated a fully automatic system which integrates classical image processing and deep neural network for segmenting WHM ...
Jiong Wu, Yue Zhang, Kai Wang, Xiaoying Tang   +3 more
doaj   +1 more source

Clinical Variability and Genotype Driven Outcomes in an International Cohort of 14 Pediatric FIG4 Patients

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Biallelic FIG4 variants classically cause distinct conditions characterized by peripheral neuropathy (Charcot‐Marie‐Tooth disease type 4J) or skeletal dysplasia (Yunis‐Varón syndrome). However, central nervous system involvement is increasingly recognized. The prevalence and specific characteristics of movement disorders within FIG4‐
Andrea Gangfuß, Vykuntaraju K. Gowda, Daniel Natera‐de Benito, Pinki Munot, Maria Vanegas, Alejandra Darling, Constanze Reutlinger, Laura Carrera‐Garcia, Gilbert Wunderlich, Heike Kölbel, Burkhard Stüve, David Muhmann, Lucía Monfort Belenguer, Diana‐Gabriela Barca, Viveka Santhosh Reddy C, Varunvenkat M. Srinivasan, Cristina Molina Anguita, Heinz Jungbluth, Hormos Salimi Dafsari, Thomas Rossor, Johann Böhm, Ulrike Schara‐Schmidt, Andreas Roos   +22 more
wiley   +1 more source

Deep white matter hyperintensities, microstructural integrity and dual task walking in older people

Brain Imaging and Behavior, 2018
To examine neural, physiological and cognitive influences on gait speed under single and dual-task conditions. Sixty-two community-dwelling older people (aged 80.0 ± 4.2 years) participated in our study. Gait speed was assessed with a timed 20-meter walk under single and dual-task (reciting alternate letters of the alphabet) conditions.
Ghanavati, T, Smitt, MS, Lord, SR, Sachdev, PS, Wen, W, Kochan, NA, Brodaty, H, Delbaere, K   +7 more
openaire   +3 more sources

Association of P-wave terminal force in lead V₁ (PTFV₁) with white matter hyperintensity volume (n = 1172).

, 2018
Association of P-wave terminal force in lead V1 (PTFV1) with white matter hyperintensity volume (n = 1172).
Ralph L. Sacco (197580), Madeleine D. Hunter (5851277), Clinton B. Wright (676702), Hooman Kamel (839731), Marco R. Di Tullio (666456), Yeseon Park Moon (5851280), Jose Gutierrez (30524), Charles DeCarli (418756), Mitchell S. V. Elkind (507634)   +8 more
core   +1 more source

Astrocytic Ketogenesis Protects Central Nervous System Injury via CPT1A Stabilization and Epigenetic Regulation

Advanced Science, EarlyView.
A distinct astrocyte subpopulation, enriched at the lesion border, drives CNS repair through enhanced ketone body metabolism. This process promotes neuronal survival and axonal sparing via CPT1A stabilization and H3K9bhb‐dependent epigenetic reprogramming, positioning astrocytic ketogenesis as a promising therapeutic target for tissue regeneration ...
Dishui Pan, Haoming Shu, Rui Gao, Yilong Ren, Wu Ye, Xuhui Ge, Yao Gu, Yufeng Zhu, Xiaokun Wang, Honglin Teng, Xuhui Zhou, Wei Liu, Yang Gao, Jianquan Zhao, Weihua Cai   +14 more
wiley   +1 more source

Data of White matter hyperintensity shape and location feature analysis on brain MRI; proof of principle study in patients with diabetes

, 2023
Anonymized MRI data and white matter hyperintensity (WMH) segmentations from the Utrecht Vascular Cognitive Impairment Study Group. Questions can be addressed to the Utrecht Vascular Cognitive Impairment Study Group Data Access Committee.
Kuijf, Hugo, Biessels, Geert Jan
core   +2 more sources

Analysis of laboratory examination and non-specific imaging changes in patients with neurosyphilis

Chinese Journal of Contemporary Neurology and Neurosurgery
Objective To investigate the clinical manifestations, laboratory examination, and non-specific imaging changes in patients with neurosyphilis (NS). Methods The clinical laboratory and brain MRI data of 31 patients with syphilis from January 2016 to ...
FENG Ai-jun, FEI Shi-zao, CHEN Zong-sheng, YU Ling, CHEN Xian-wen   +4 more
doaj   +1 more source

A New Classification System for Ischemia Using a Combination of Deep and Periventricular White Matter Hyperintensities

Journal of Stroke and Cerebrovascular Diseases, 2014
The Clinical Research Center for Dementia of South Korea (CREDOS) group developed a new classification system for ischemia using a combination of deep and periventricular white matter hyperintensities (WMHs). In this study, we aimed to evaluate the validity of the CREDOS ischemia classification system. A total of 352 patients with cognitive impairments
Young, Noh, Yunhwan, Lee, Sang Won, Seo, Jee H, Jeong, Seong Hye, Choi, Joung Hwan, Back, Sook-Young, Woo, Geon Ha, Kim, Ji Soo, Shin, Chi Hun, Kim, Hanna, Cho, Joon Sung, Park, Jong-Min, Lee, Chang Hyung, Hong, Sang Yun, Kim, Jae-Hong, Lee, Seong Yoon, Kim, Kee Hyung, Park, Seol-Heui, Han, Hae-Kwan, Cheong, Duk L, Na   +20 more
openaire   +3 more sources

WSO895707 Supplemental Material - Supplemental material for Normal-appearing white matter microstructural injury is associated with white matter hyperintensity burden in acute ischemic stroke

, 2019
Supplemental material, WSO895707 Supplemental Material for Normal-appearing white matter microstructural injury is associated with white matter hyperintensity burden in acute ischemic stroke by Mark R Etherton, Ona Wu, Anne-Katrin Giese and Natalia S ...
Mark R Etherton (8155041), Natalia S Rost (8155044), Ona Wu (464087), Anne-Katrin Giese (440558)   +3 more
core   +1 more source

AI‐Based Mitochondrial Network Characterization as a Biomarker for DNM1L‐Related Disease Diagnosis

Advanced Intelligent Systems, EarlyView.
This work provides proof‐of‐concept that AI‐based analysis of mitochondrial network morphology in patient‐derived fibroblasts can identify a phenotypic signature associated with DNM1L deficiency. This automated approach may ultimately provide a complementary functional readout for the interpretation of novel DNM1L variants following genetic testing ...
Uliana Musokhranova, Ioannis Georvasilis, Sofía Illescas, Matina Saritzoglou, Marcos Frías, Mònica Roldán, Anna Ardissone, Isabella Moroni, Àngels García‐Cazorla, Alfonso Oyarzábal   +9 more
wiley   +1 more source