Results 191 to 200 of about 7,638,076 (261)

Atherosclerosis: From Pathogenesis to Therapeutic Interventions

MedComm, Volume 7, Issue 11, November 2026.
The diagram outlines the core mechanisms driving atherosclerosis, including endothelial dysfunction, inflammatory responses, phenotypic switching of smooth muscle cells, and the gut–vascular axis. It also presents the corresponding therapeutic approaches now under development, such as gene therapies, immunotherapies, and nanotechnology platforms ...
Enge Zhou, Chenxi Zhan, Yuting Li, Yi Zeng, Renfei Luo, Xin Ouyang, Shixing Liu, Renqiang Yang, Nianlong Yan, Long Jiang   +9 more
wiley   +1 more source

Volumetric and Intrastructural Characterization of the Substantia Nigra Using Optimized Synthetic MR Images Derived From Quantitative T1 Maps at 3 T

NMR in Biomedicine, Volume 39, Issue 11, November 2026.
Automated segmentation using the NextBrain atlas and synthetic MRI effectively overcomes systematic age‐related biases observed in manual delineation of the substantia nigra. A novel qT1‐based synthetic contrast utilizing signal‐increased pseudo‐proton spin density (pPSD) provides improved intrastructural separation of nigral subregions (SNpc and SNpr)
Lukas von Erdmannsdorff, Lora Kovacheva, Dennis C. Thomas, Elke Hattingen, Ralf Deichmann, Christophe Théo Arendt   +5 more
wiley   +1 more source

Suboccipital transhorizontal fissure approach for a deep-seated pediatric cerebellar tumor: illustrative case. [PDF]

J Neurosurg Case Lessons
Kojima M, Tamura R, Nishimoto M, Iinuma T, Ueda R, Toda M.   +5 more
europepmc   +1 more source

Dorsal ischaemic myelopathy in a dog: A case of unilateral, focal predominantly sensory loss

Veterinary Record Case Reports, Volume 14, Issue 4, November 2026.
Abstract A 3‐year‐3‐month‐old, neutered, male Great Dane was presented with peracute left hindlimb monoparesis. Although voluntary movement was present, the dog was effectively non‐ambulatory due to its size. Proprioception, nociception and spinal reflexes were absent in the left hindlimb, localising the lesion to a left L4–S1 myelopathy.
Alexandra Ayoub, Ana Maria Oliveira, Nicholas Goody, Aran Nagendran   +3 more
wiley   +1 more source

Clinical and MRI findings of suspected cerebrospinal nematodiasis in an alpaca

Veterinary Record Case Reports, Volume 14, Issue 4, November 2026.
Abstract A 5‐year‐old alpaca was presented with a 2‐week history of progressive pelvic limb ataxia and paresis. Neurological examination localised the lesion to the thoracolumbar spinal cord. Magnetic resonance imaging (MRI) of the cervical and thoracolumbar spine revealed no abnormalities; however, contrast‐enhanced sequences were not performed due to
Aurelia Gasser, Mireille Meylan, Alexane Durand, Veronika Stein, Arianna Maiolini   +4 more
wiley   +1 more source

An Interpretable Multimodal Machine-Learning Model for Predicting Cognitive Impairment from Routine MRI: A Study with External Validation. [PDF]

Bioengineering (Basel)
Chen X, Zhang B, Li M, Wang S, Yang M, Zhang J, Zhu X, Kang Y, Tan W.   +8 more
europepmc   +1 more source

Patient‐derived surgical samples reveal the cellular and molecular signatures of glioblastoma infiltration in distinct radiological zones

Brain Pathology, Volume 36, Issue 6, November 2026.
Integrated histological and transcriptional profiling of the glioblastoma periphery reveals clinically relevant tumor infiltration beyond MRI‐defined boundaries. MRI‐guided biopsies from contrast‐enhancing (CE), non‐contrast‐enhancing (nCE), edema (E), and radiologically normal (N) regions demonstrate that nCE areas frequently retain neoplastic and ...
Olaya de Dios, Juan Romero, María de los Ángeles Ramírez‐González, Beatriz Herranz, Alicia Avis‐Bodas, Juliana Manosalva, Diego Megías, Ana Ramos, Juan Manuel Sepúlveda‐Sánchez, Ricardo Gargini, Berta Segura‐Collar, Gabriel Velilla, Bárbara Meléndez, Pedro González, Luis Jiménez‐Roldán, Guillermo García‐Posadas, Aurelio Hernández‐Laín, Ángel Pérez‐Núñez, Pilar Sánchez‐Gómez   +18 more
wiley   +1 more source

Paralytic Rabies Encephalomeningomyelitis: A Tale of Two Cases With Emphasis on Imaging Findings and Relevant Literature Review. [PDF]

Cureus
Kedar K, Patel AV, Ratnaparkhi C, Dhok A, Kumbhalkar S.   +4 more
europepmc   +1 more source

Dysregulated TIE‐2 expression is associated with blood‐brain barrier leakiness and Alzheimer's disease‐related neuropathology

Brain Pathology, Volume 36, Issue 6, November 2026.
Ince et al., have analysed TIE‐1 and ‐2 expression in human brain tissue, including microvessel‐enriched fractions (MVF) and covering a spectrum of AD‐associated pathology, and in CSF from independent cohorts spanning a clinical spectrum from normal cognition to AD.
Selvi Ince, Carol Van Hulle, Gwendlyn Kollmorgen, Clara Quijano‐Rubio, Carey Gleason, Barbara B. Bendlin, Ozioma Okonkwo, Sanjay Asthana, Kaj Blennow, Henrik Zetterberg, Sterling C. Johnson, Seth Love, J. Scott Miners   +12 more
wiley   +1 more source

Multiple Sclerosis Misdiagnosis in Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy: A Genotype-Misphenotype Study. [PDF]

Neurol Genet
Mendis DD, Vallamchetla SK, Marin Collazo IV, Sandhu SJS, Meschia JF.   +4 more
europepmc   +1 more source