Results 201 to 210 of about 7,638,076 (261)

Wasteosomes accumulate in periventricular white matter hyperintensities and exhibit complex relationships with mixed pathology, sclerotic index, and perivascular space

Brain Pathology, Volume 36, Issue 6, November 2026.
In a mixed diagnostic cohort of pathologically diagnosed Alzheimer's disease, cerebrovascular disease, mixed pathology, and control tissue, we connected the histopathological wasteosome profile in periventricular (PV) brain sections to 7T FLAIR‐MRI confirmed PV white matter hyperintensities (WMHs), vascular stenosis and perivascular space size ...
Nikita Ollen‐Bittle, Isabella Boesgaard, Austyn Roseborough, Meaghan Frank, Qi Zhang, Stephen H. Pasternak, Robert Hammond, Shawn N. Whitehead   +7 more
wiley   +1 more source

Magnetic resonance imaging in leukodystrophies: characteristic patterns and diagnostic relevance. [PDF]

Arq Neuropsiquiatr
Ruffini ML, Pereira DA, Helmer RS, Souza AM, Lima BS, Baccarin G, Yamada GK, Borella LFM, Turci RD, Duarte JÁ, Reis F.   +10 more
europepmc   +1 more source

Subclinical Cerebral Lesions in Migraine: A Proof‐of‐Concept Study on Platelet Aggregation

European Journal of Neurology, Volume 33, Issue 11, November 2026.
We assessed platelet aggregation in patients with migraine (n = 34) with or without cerebral white‐matter lesions (WMLs) versus matched controls (n = 34), with WMLs volume quantified by MRI (mm3). Aggregation to ADP, collagen, epinephrine, and arachidonic acid was measured; epinephrine‐induced aggregation at 1.25–2.5 μM was overall lower in migraine ...
Ilaria Maestrini, Mariaignazia Curreli, Marta Puma, Costanza Giannì, Eleonora Schiera, Giada Giuliani, Massimiliano Toscano, Marta Altieri, Patrizia Pantano, Fabio Pulcinelli, Vittorio Di Piero   +10 more
wiley   +1 more source

Recognising Mild Cognitive Impairment and Early Alzheimer's Disease in General and Psychiatric Practice: Clinical Clues and Appropriate Referral

Psychogeriatrics, Volume 26, Issue 6, November 2026.
ABSTRACT Early cognitive decline may become evident through changes in daily activities or behaviour before it is apparent in a brief consultation. This selective narrative review supports case‐finding and appropriate referral in general and psychiatric practice.
Kengo Shimoda
wiley   +1 more source

The relationship between white matter hyperintensity and gait in patients with cerebral small vessel disease. [PDF]

Front Neurol
Wang Y, Zhu Z, Zhao J, Liu S.
europepmc   +1 more source

Cerebral blood flow regulation, central arterial stiffness and traumatic brain injury: Effects of aerobic exercise training

Experimental Physiology, Volume 111, Issue 11, Page 5032-5040, 1 November 2026.
Abstract Advanced age is the strongest risk factor for Alzheimer's disease and related dementias (ADRDs). Traumatic brain injury (TBI) has also been recognized as a risk factor for ADRD, potentially contributing to an earlier onset of the disease. Thus, elucidating the mechanisms underlying brain ageing and TBI is critical for developing strategies to ...
Tsubasa Tomoto, Kan Ding, C. Munro Cullum, Rong Zhang   +3 more
wiley   +1 more source

The mediating role of white matter hyperintensity in the association between malnutrition and cognitive impairment in patients with cerebral small vessel disease. [PDF]

Front Neurol
Luo W, Zhang G, Lu M, Bu W, Yang L, Yang Y, Ren H.   +6 more
europepmc   +1 more source

Impact of White Matter Hyperintensities on Reperfusion Injury and Clinical Outcome After Successful Recanalization. [PDF]

Stroke Vasc Interv Neurol
Nishimoto T, Oka F, Kawano R, Fujitsuku S, Mori N, Kawano A, Ishihara H.   +6 more
europepmc   +1 more source

Digital completion time relates more strongly to Alzheimer's disease-type atrophy than to vascular burden in a community cohort. [PDF]

Alzheimers Dement (Amst)
Iwasa K, Omori N, Ishida M, Tanaka T, Nagai A.   +4 more
europepmc   +1 more source

A 58‐year‐old woman experiencing occasional dizziness, impaired awareness, and deep feeling of fear

Brain Pathology, Volume 36, Issue 6, November 2026.
Alessandro Selvaggini, Sabrina Rossi, Marco Brollo, Sabina Barresi, Laurino Licia, Lorenzo Nicolè   +5 more
wiley   +1 more source