Results 101 to 110 of about 1,902,450 (297)

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Two laser-assisted hatching methods of embryos in ART: a systematic review and meta-analysis

BMC Pregnancy and Childbirth
Background Laser-assisted hatching (LAH) stands as the predominant technique for removing the zona pellucida (ZP) in embryos, primarily consisting of two methods: drilling laser-assisted hatching (D-LAH) and thinning laser-assisted hatching (T-LAH ...
Kexin Chen, Mengying Gao, Yao Wu, Zhixin Hu, Lu Tang, Minyao Li, Mei Tian, Hao Cui, Yanrong Huang, Youzhen Han, Lei Li, Yonggang Li, Yunxiu Li, Ze Wu, Zouying Tang, Ronghui Zhang, Yuerong Wu, Yizhi Zhang, Yan Guo, Hongqing Zhang, Lifeng Xiang, Jiacong Yan   +21 more
doaj   +1 more source

Prenatal diagnosis of BACs‐on‐Beads assay in 1520 cases from Fujian Province, China

Molecular Genetics & Genomic Medicine, 2020
Background The aim of this study was to evaluate the application of BACs‐on‐Beads (BoBs™) assay for rapid detection of chromosomal abnormalities for prenatal diagnosis (PND). Methods A total of 1520 samples, including seven chorionic villi biopsy samples,
Yan Wang, Min Zhang, Lingji Chen, Hailong Huang, Liangpu Xu   +4 more
doaj   +1 more source

Defect-induced phase transition in the asymmetric simple exclusion process

, 2015
We reconsider the long-standing question of the critical defect hopping rate $r_c$ in the one-dimensional totally asymmetric exclusion process (TASEP) with a slow bond (defect).
Popkov, Vladislav, Schadschneider, Andreas, Schmidt, Johannes   +2 more
core   +1 more source

Transdimensional defects

Journal of High Energy Physics
Abstract This note introduces a novel paradigm for conformal defects with continuously adjustable dimensions. Just as the standard ε expansion interpolates between integer spacetime dimensions, a new parameter, δ, is used to interpolate between different integer-dimensional defects.
Elia de Sabbata, Nadav Drukker, Andreas Stergiou   +2 more
openaire   +3 more sources

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

The diagnostic accuracy of preimplantation genetic testing (PGT) in assessing the genetic status of embryos: a systematic review and meta-analysis

Reproductive Biology and Endocrinology
Background Preimplantation genetic testing (PGT) is widely used in assisted reproduction to assess the genetic status of embryos. However, increasing evidence suggests that the trophectoderm (TE) may not fully reflect the genetic status of the inner cell
Kexin Chen, Zhixin Hu, Yuxuan Lian, Youzhen Han, Xiaoting Zhou, Yonggang Li, Lifeng Xiang, Weiqun Jiang, Mingying Li, Peng Zeng, Manqin Zhang, Xi Luo, Yongfang Xu, Haishan Zheng, Mei Tian, Mei Wang, Rui Ma, Jichun Yang, Yun Bai, Ruiyu Du, Bo Deng, Ze Wu, Yunxiu Li, Jiacong Yan   +23 more
doaj   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

The role of mitochondrial dysfunction in ovarian granulosa cells in polycystic ovary syndrome

Endocrine Connections
Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder that significantly impacts women’s reproductive capabilities and metabolic health, leading to a range of complications that can affect their quality of life.
Xuejun Yan, Dan Ma, Rongnian Li, Jing Xu, Ying Zou, Minmin He   +5 more
doaj   +1 more source