Results 41 to 50 of about 1,659 (296)

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Millimeter-wave Defected Ground Structure-based MIMO Antenna for 6G Wireless Applications [PDF]

, 2023
In this paper, a 2×2 multiple-input-multiple-output (MIMO) assembly of an elliptical-shaped millimeter-wave (mm-wave) antenna with defected-ground structures (DGS) is presented.
Alkaraki, Shaker, Jilani, Syeda Fizzah, Abbasi, Qammer H., Griffiths, Gabriela Jana, Evans, Andrew, Aslam, Muhammad   +5 more
core   +1 more source

Research on the Defected Ground Structure With Von Koch Snowflake Fractals [PDF]

IEEE Access, 2020
This paper studies the electromagnetic properties of defected ground structure (DGS) with von Koch snowflake fractals. First, the snowflake fractal is employed in the dumbbell shaped DGS, and we have discovered that it has the characteristics of a low-pass filter and the out-of-band rejection increases with fractal iterations.
Xin Cao 0003, Bowen Luo, Yuyu Zhu, Zuxue Xia, Qiangming Cai   +4 more
openaire   +2 more sources

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Planar fractal filter on defected ground substrate

, 2012
The diploma thesis is focused on the design of planar filters combining fractal layouts and defected ground substrates. The diploma thesis can be divided into three main parts.
Kufa, Martin
core   +1 more source

Enhanced Quadrature Hybrid Coupler Design for 5G N1 Band Using Defected Ground Structures

Jurnal Nasional Teknik Elektro
This study addresses the performance limitations of conventional hybrid couplers used in sub-6 GHz 5G infrastructure, targeting the N1 band (1.92–2.17 GHz), and integrates Defected Ground Structure (DGS) technology. The objective is to enhance bandwidth,
Rudy Fernandez, Amirul Luthfi, Syukri Yunus, Tiara Feryndita Astuti   +3 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Slow-wave CPW resonator with defected ground structure (DGS) for filter applications [PDF]

, 2006
Novel slow-wave CPW resonators with defected ground structures (DGSs) in a rectangularly spaced and open-loop shapes are investigated. These structures have an extremely compact size.
Gorur, A, Akgün, Özlem, Akgun, O, Görür, Adnan   +3 more
core   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source