Results 31 to 40 of about 1,685,969 (303)
Crystalline silicon (Si) is the key material of the semiconductor industry, with significant applications for electronic and microelectronic devices. The properties of Si are affected by impurities and defects introduced into the material either during ...
Charalampos A. Londos +5 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
High Expression of VAV Gene Family Predicts Poor Prognosis of Acute Myeloid Leukemia
Objectives: VAV family genes ( VAV1, VAV2, and VAV3 ) are associated with prognosis in various cancers; however, they have not been evaluated in acute myeloid leukemia (AML). In this study, the prognostic value of VAV expression in AML was evaluated by a
Dan Mu BA +3 more
doaj +1 more source
Modeling of Deformation and Destruction Processes of Al/Cu Nanocomposites
The aim of this work is to carry out molecular dynamics simulation of the uniaxial stretching of a cooled Al/Cu composition. The LAMMPS software package has been used for calculations, which includes the classic molecular dynamics code with an emphasis ...
A. V. Vakhrushev +2 more
doaj +1 more source
Influence of radiation defects on the electrophysical and detector properties of CdTe:Cl irradiated by neutrons [PDF]
A promising material for semiconductor detectors of ionizing radiation is CdTe:Cl which allows obtaining detectors with high resistivity ρ and electron mobility μn.
Kondrik A. I., Kovtun G. P.
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Inhibition of GOT1 potentiates ferroptosis and exacerbates cell death in acute myeloid leukemia
Background Drug resistance, poor treatment response, and low long-term survival rates are major obstacles to the successful long-term treatment of acute myeloid leukemia (AML), a heterogeneous hematologic malignancy.
Huan Peng +7 more
doaj +1 more source
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Objective. Improving diagnostic ability of pediatric sepsis is of great significance for reducing the mortality of sepsis. This study explored the discriminatory capacity of nutritional index (PNI) in pediatric sepsis. Methods.
Deng Hongya MBBS +6 more
doaj +1 more source

