Results 91 to 100 of about 9,269,203 (381)

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

The Mediating Role of Defensive Mechanisms in the Relationship between Social Phobia and Alexithymia in University Students

open access: yesJournal of Holistic Nursing and Midwifery, 2020
Introduction: Psychological factors play a key role in peoplechr('39')s emotional responses to different social situations.  Objective: This study aimed to investigate the mediating role of defense mechanisms in the relationship between social phobia and
Mansour Nasiri   +2 more
doaj  

A Neural Model of How The Brain Represents and Compares Numbers [PDF]

open access: yes, 1999
Many psychophysical experiments have shown that the representation of numbers and numerical quantities in humans and animals is related to number magnitude.
Grossberg, Stephen, Repin, Dmitry
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

The assessment of stress level, anxiety, depressive symptoms, and defense mechanisms among Polish and English medical students

open access: yesAnnals of General Psychiatry, 2020
Introduction Medical education is proven to be associated with a high degree of psychological stress. Different coping strategies used by students have been investigated on their efficacy. So far, studies on medical students have been limited to a single
M. Pawlaczyk   +3 more
doaj   +1 more source

Pricing and Investments in Internet Security: A Cyber-Insurance Perspective [PDF]

open access: yes, 2011
Internet users such as individuals and organizations are subject to different types of epidemic risks such as worms, viruses, spams, and botnets. To reduce the probability of risk, an Internet user generally invests in traditional security mechanisms ...
Golubchik, Leana, Pal, Ranjan
core  

Adverse effects of microplastics and oxidative stress-induced MAPK/Nrf2 pathway-mediated defense mechanisms in the marine copepod Paracyclopina nana

open access: yesScientific Reports, 2017
Microplastic pollution causes a major concern in the marine environment due to their worldwide distribution, persistence, and adverse effects of these pollutants in the marine ecosystem.
Chang-Bum Jeong   +10 more
semanticscholar   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Defense mechanisms in psychological health and sport success of athletes [PDF]

open access: yesJournal of Kerman University of Medical Sciences, 2017
Introduction: Defense mechanisms represent a crucial component of our capacity to maintain emotional homeostasis. The present study is carried out with the purpose of determining the predictability of psychological health and sport success by defense ...
Afrooz Mousavi   +2 more
doaj  

Exploring clusters of defense styles, psychiatric symptoms and academic achievements among medical students: a cross-sectional study in Pakistan

open access: yesBMC Research Notes, 2018
Objective The clusters of participants with a homogeneous psychological make-up can be identified using sophisticated machine learning techniques such as the two-step clustering algorithm.
Ahmed Waqas   +4 more
doaj   +1 more source

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