Results 141 to 150 of about 54,233 (258)

Innate Lymphoid Cells in Tissue Homeostasis and Diseases

open access: yesMedComm, Volume 7, Issue 5, May 2026.
Innate lymphoid cells (ILCs) are a heterogeneous group of immune cells with phenotypic and functional plasticity. ILCs dynamically regulate various immune cell types and play a crucial role in the pathophysiological processes of specific organs during sepsis. Targeting ILCs is a promising strategy for treating sepsis.
Zhenzhen Zhan   +7 more
wiley   +1 more source

Isolation, Identification and Pathogenicity Analysis of Proteus mirabilis in Cynomolgus Monkey From Yunnan, China

open access: yesVeterinary Medicine and Science, Volume 12, Issue 3, May 2026.
This study demonstrated that the pathogen responsible for diarrhoea in a cynomolgus monkey was identified as Proteus mirabilis (P. mirabilis) through methods including bacterial isolation and culture, morphological examination, biochemical profiling, 16S rRNA sequencing, analysis of key virulence genes and bacterial artificial infection tests.
Heling Li   +6 more
wiley   +1 more source

[Scorpion toxins and defensins].

open access: yesComptes rendus des seances de la Societe de biologie et de ses filiales, 1998
Les venins de scorpion contiennent un grand nombre de neurotoxines peptidiques qui constituent un ensemble de familles molécu­laires à haut degré de polymorphisme, mais qui ont en commun une architecture semblable. Cette architecture se retrouve dans des peptides antibactériens circulants de la famille des défensines, qui s'apparentent tout ...
Goyffon, M, Landon, C.
openaire   +2 more sources

A Botanical Mixture of Boswellia serrata, Commiphora myrrha, Propolis and Scutellaria baicalensis Reduces Expression of Inflammatory Chemokines in Canine Keratinocytes In Vitro

open access: yesVeterinary Medicine and Science, Volume 12, Issue 3, May 2026.
YSK‐AB, a botanical mixture, reduced nitric oxide production in RAW 264.7 cells and chemokine expression in canine keratinocytes, suggesting its potential as a natural therapeutic agent for inflammatory skin diseases in dogs. ABSTRACT Background Botanical ingredients can function as adjunctive therapies for managing inflammatory skin diseases ...
Danbee Ha   +3 more
wiley   +1 more source

Decellularized Aged Bruch's Membrane Confers Unique Biochemical Cues to Retinal Pigment Epithelium for In Vitro Modeling of Age‐Related Macular Degeneration

open access: yesAging Cell, Volume 25, Issue 5, May 2026.
A Bruchs membrane (BrM) mimic based on aged decellularized BrM was developed and differentially expressed proteins in aged dECM‐BrM that may provide specific biochemical cues fundamental to model AMD in vitro were identified. RPE culture on aged dECM‐BrM developed certain AMD‐like features including reduced TEER and expression of drusen components ...
Blanca Molins   +8 more
wiley   +1 more source

Beyond the Barrier: Epithelial Cells as Immune Sentinels in the Female Genital Tract

open access: yesAmerican Journal of Reproductive Immunology, Volume 95, Issue 5, May 2026.
ABSTRACT Epithelial cells (ECs) of the female genital tract (FGT) serve as an essential barrier and the first line of defense against sexually transmitted pathogens. Beyond providing a physical barrier, these cells actively contribute to immune responses through pathogen recognition, cytokine release, and modulation of adaptive immune responses ...
Lauren Jirik   +3 more
wiley   +1 more source

Anaerobe‐Driven Inflammation and Epithelial Barrier Disruption in Genital HIV Acquisition

open access: yesAmerican Journal of Reproductive Immunology, Volume 95, Issue 5, May 2026.
ABSTRACT Background Genital microbiome dysbiosis is an important risk factor for the sexual acquisition of human immunodeficiency virus (HIV) in both the male and female genital tracts. The vaginal, penile and urethral mucosae are distinct microenvironments with characteristic microbiome compositions.
Shirley Constable   +6 more
wiley   +1 more source

Exploring the multifaceted roles of beta-defensins in prediabetes: a detailed review. [PDF]

open access: yesFront Endocrinol (Lausanne)
Almansour N   +3 more
europepmc   +1 more source

Innate Immunity and Microbial Recognition in Reproduction: From Barrier Defense to Maternal–Fetal Tolerance

open access: yesThe FASEB Journal, Volume 40, Issue 8, 30 April 2026.
Graphical abstract illustrating the barrier defense–tolerance framework of reproductive innate immunity. Across the female and male reproductive tracts and the maternal–fetal interface, epithelial barriers, innate sensors, immune cells, and microbial signals are integrated to preserve reproductive homeostasis.
Xianlin Rao   +3 more
wiley   +1 more source

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