Results 101 to 110 of about 32,113 (291)

New opportunities for bioscaffold‐enabled spinal cord injury repair

BMEMat, EarlyView.
Schematic illustration of bioscaffolds for spinal cord injury repair. We summarize the effects of bioscaffold properties on SCI repair, highlight different types of bioscaffolds, various fabrication strategies, and in vivo transformations for the clinical development of SCI‐repairing bioscaffolds.
Xiaoqing Qi, Yicheng Fu, Zhaoliang Su, Li Li, Subrata Chakrabarti, Peng Li, Yilun Wu, Fang Liu, Teng Gao, Zhifeng Dong, Lei Liu, Pei Cao   +11 more
wiley   +1 more source

Improving adherence with deferoxamine regimen in thalassemia major using education

Iranian South Medical Journal, 2006
Background: Subcutaneous deferoxamine is the first line for management of iron overload in thalassemia major. There is a wide deferoxamine adherence variation in patients with thalassemia major.
Gholamreza Pouladfar, Mandana Moaiedfard
doaj  

Nano‐networks via reaction‐induced self‐assembly coordinate spatiotemporal multi‐drug delivery for acute kidney injury therapy

BMEMat, EarlyView.
Multifunctional nano‐networks (NNWs) are prepared via reaction‐induced self‐assembly (RISA) of spermidine (SPD), epigallocatechin gallate (EGCG), 2‐formylphenylboronic acid (2‐FPBA), and deferoxamine (DFO) through dynamic iminoboronate bonds. These NNWs leverage the oxidative AKI microenvironment to trigger disintegration, enabling site‐specific ...
Juan Jin, Xiao Zhang, Chenxi Wang, Taian Jin, Xinyang Fang, Yixuan Gao, Mengchun Chen, Weiyang Meng, Chang Gao, Wenlu Li, Yuanfeng Li, Yijie Chen, Calvin A. Omolo, Thirumala Govender, Linqi Shi, Yunguang Wang, Yong Liu, Qiang He   +17 more
wiley   +1 more source

Ferroxitosis: a cell death from modulation of oxidative phosphorylation and PKM2-dependent glycolysis in melanoma [PDF]

, 2014
Reliance on glycolysis is a characteristic of malignancy, yet the development of resistance to BRAF inhibitors in melanoma is associated with gain of mitochondrial function.
Brustovetsky, Nickolay, Dagher, Pierre C., Dong, X. Charlie, Hamilton, James, Harris, Robert A., Hato, Takashi, Ivan, Mircea, Lakhter, Alexander J., Mayo, Lindsey D., Mukkamala, Suresh, Naidu, Samisubbu R., Shekhar, Anantha   +11 more
core   +2 more sources

Curcumin and N-Acetylcysteine Nanocarriers Alone or Combined with Deferoxamine Target the Mitochondria and Protect against Neurotoxicity and Oxidative Stress in a Co-Culture Model of Parkinson’s Disease [PDF]

, 2023
Leah Mursaleen, Stefanie Ho Yi Chan, B Noble, Satyanarayana Somavarapu, Mohammed Gulrez Zariwala   +4 more
openalex   +1 more source

NUPR1 acts as a pro-survival factor in human bone marrow-derived mesenchymal stem cells and is induced by the hypoxia mimetic reagent deferoxamine

Journal of clinical biochemistry and nutrition, 2019
Differences in the culturing conditions of mesenchymal stem cells used in regenerative medicine may affect their differentiation ability, genome instability, and therapeutic effects.
K. Matsunaga, K. Fujisawa, T. Takami, G. Burganova, Nanami Sasai, Toshihiko Matsumoto, N. Yamamoto, I. Sakaida   +7 more
semanticscholar   +1 more source

Pharmacological effects of gastrodin: Insight into neurological diseases and mechanism in ferroptosis and pyroptosis

Ibrain, Volume 11, Issue 1, Page 74-83, Spring 2025.
Pharmacological effects of gastrodin include prevention and treatment of cognitive decline and reperfusion injuries, anticonvulsion, antiepilepsy, antidepressants, and analgesia, which are related to antiferroptosis and antipyroptosis. Abstract Gastrodin, as an effective monomer of gastrodia elata, plays a significant role in anti‐inflammatory ...
Xue Zheng, Jing Li, Zhao‐Qiong Zhu
wiley   +1 more source

Comparison of Efficacy, Safety, and Humanistic Outcomes of Iron-Chelation Therapy in Pediatrics Suffering from Transfusion-Dependent β-Thalassemia Major

Indian Journal of Medical Specialities, 2020
Introduction: Beta-thalassemia major (β-TM) is a severe form of genetic disorder that affects the patient's quality of life. Iron-chelation therapy (ICT) is recommended in these patients to reduce the complications (iron overload) associated with ...
Narayana Goruntla, P. Stephen Azarya, Mahitha Chalagundla, Dasaratha Ramaiah Jinka, Pradeepkumar Bhupalam, Vishnuvandana Bandaru   +5 more
doaj   +1 more source

Targeting Pro-Oxidant Iron with Deferoxamine as a Treatment for Ischemic Stroke: Safety and Optimal Dose Selection in a Randomized Clinical Trial [PDF]

, 2021
Mónica Millán, Núria DeGregorio‐Rocasolano, Natàlia Pérez de la Ossa, Sílvia Reverté‐Villarroya, Joan Costa‐Font, Pilar Giner, Yolanda Silva, Tomás Sobrino, Manuel Rodríguez‐Yáñez, Florentino Nombela, Francisco Campos, Joaquı́n Serena, José Vivancos, Octavi Martí‐Sistac, Jordi Cortés, Antoni Dávalos, Teresa Gasull   +16 more
openalex   +1 more source

Co-delivery of deferoxamine and hydroxysafflor yellow A to accelerate diabetic wound healing via enhanced angiogenesis

Drug Delivery, 2018
Nonhealing chronic wounds on foot induced by diabetes is a complicated pathologic process. They are mainly caused by impaired neovascularization, neuropathy, and excessive inflammation.
Siqian Gao, Chen Chang, Jun-Jun Li, Y. Li, Xiao-Qian Niu, Danping Zhang, Long-Jian Li, Jianqing Gao   +7 more
semanticscholar   +1 more source