Results 101 to 110 of about 1,195,963 (357)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Changes of methylation at enhancers appear to be essential for HIV infection progression

Clinical Epigenetics
Background We studied the influence of the European HIV-1 subtype B (most common in the Western and Central Europe) and subtype A6 (prevalent in Eastern Europe including Ukraine and Russia) on host methylome during infection progression and in virus ...
Olga Taryma-Leśniak, Jan Bińkowski, Kaja Mielczak, Bogusz Aksak-Wąs, Malwina Karasińska-Cieślak, Marta Sobalska-Kwapis, Dominik Strapagiel, Miłosz Parczewski, Tomasz Kazimierz Wojdacz   +8 more
doaj   +1 more source

Modeling CSF-1 receptor deficiency diseases - how close are we? [PDF]

FEBS J, 2022
Chitu V, Gökhan Ş, Stanley ER.
europepmc   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Azolla pinnata mitigates pendimethalin induced immunotoxicity, oxidative stress and histopathological changes in Oreochromis niloticus

Scientific Reports
Aquatic animals face multiple threats, including pesticides, heavy metals, and other environmental pollutants, risking their health and survival. Limited bioremediation studies have been conducted on the detrimental impacts of herbicides on fish.
Nagwa I. S. Abu-Zahra, Mofeed Gouda, Mohamed M. Elseify, Mona E. Abass, Mohammed S. El-Gohary, Eman T. El-sokary   +5 more
doaj   +1 more source

Vitamin D sufficiency and the effect of its deficiency on the course of allergic diseases in children [PDF]

, 2022
Yu.V. Marushko, S.I. Yesipova, T.V. Hyshchak, N.S. Boyko   +3 more
openalex   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

[Regional target program «Prevention of iodine deficiency diseases for 202X-202X»]. [PDF]

Probl Endokrinol (Mosk), 2022
Troshina EA, Platonova NM, Makolina NP, Belovalova IM, Senyushkina ES, Melnichenko GA, Dedov II.   +6 more
europepmc   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Outcomes with third-party virus-specific T cells after the use of single-antigen cell lines to predict HLA restriction

Blood Advances
: Patients with significant T-cell dysfunction from chemotherapy or hematopoietic stem cell transplant are at significant risk for complications of viral infections.
Jeremy D. Rubinstein, Giang Pham, Anusha Sridharan, Ruby Khoury, YunZu M. Wang, Zahra Hudda, Jamie Wilhelm, Daniel A. Lichtenstein, Daria Heyenbruch, Jose A. Cancelas, Stella M. Davies, Carolyn Lutzko, Michael S. Grimley   +12 more
doaj   +1 more source