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Complement Deficiency and Disease
Australian and New Zealand Journal of Medicine, 1982: The complement system consists of a series of serum proteins which interact to facilitate the action of certain classes of antibody and antigen/antibody complexes. Complement may be disturbed by pathological utilisation of one or both of its pathways or by a primary deficiency of an individual component.
J A, Charlesworth, B A, Pussell
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Deficiency Diseases in the Caribbean
Journal of Interdisciplinary History, 1980Deficiency Diseases in the Caribbean The historiography of slavery in the Americas has recently taken on a new biological dimension as historians have begun to appreciate the importance of pathogenic agents in any holistic understanding of their subject.
K F, Kiple, V H, Kiple
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Sleep Deficiency and Cardiometabolic Disease
Sleep Medicine Clinics, 2022Epidemiologic studies have demonstrated that short sleep duration is associated with an increased risk of cardio-metabolic health outcomes including cardiovascular disease mortality, coronary heart disease, type 2 diabetes mellitus, hypertension, and metabolic syndrome. Experimental sleep restriction studies have sought to explain these findings.
Roo, Killick +2 more
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Complement deficiency and disease
Journal of Clinical Pathology, 2008There are approximately 30 serum complement proteins (15% of the globulin fraction), excluding cell surface receptors, and regulatory proteins. Many are manufactured in the liver, and reduced complement is a feature of severe liver failure. Complement proteins contribute to the acute phase response, and high levels are seen in chronic untreated ...
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Trypsinogen deficiency disease
The Journal of Pediatrics, 1964An infant with severe growth failure, hypoproteinemia, and edema is described. Clinical and laboratory studies indicate that this disorder results from an impaired capacity to hydrolyze ingested protein. By means of specific pancreatic proteolytic enzyme assays, it was established that the primary defect is a complete absence of trypsinogen. Absence of
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MAGNESIUM DEFICIENCY IN CELIAC DISEASE
Pediatrics, 1962Balance studies were performed on a 16½-year-old white girl with hypomagnesemia due to celiac disease. During the initial phase of the study, a great magnesium loss in feces was demonstrated, with decreased magnesium excretion in urine and increased sodium and potassium retentions.
A S, GOLDMAN +2 more
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Complement deficiencies and human diseases
Annales de biologie clinique, 2014The complement system is a complex system involving serum and membrane proteins interacting in a regulated manner. The complement system plays a major role in antibacterial immunity, in inflammation, and in immune complex processing. Therefore, deficiencies in complement proteins are associated with increased susceptibility to bacterial infections and ...
Jérémie, Rosain +7 more
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Complement deficiency and disease: An update
Molecular Immunology, 2006Complement deficiencies are probably vastly under-diagnosed within clinical medicine. Judging from a Swedish study of C2 deficiency, a deficiency with an estimated prevalence of about 1/20,000 in Western countries, less than 10% of the deficiencies of the classical and alternative pathways and the late complement components are identified in Sweden. C1
A G, Sjöholm +4 more
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Copper Deficiency in Celiac Disease
Journal of Clinical Gastroenterology, 2009Copper deficiency is an uncommonly reported complication of celiac disease that has not received much attention in recent years. Copper deficiency may result in anemia and thrombocytopenia and also irreversible myeloneuropathy if it is not detected and treated appropriately. The prevalence of copper deficiency in patients with celiac disease is unknown.
Thorvardur R, Halfdanarson +3 more
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