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Pharmacoepidemiological research about antibiotics is supported by the World Health Organization (WHO), but data regarding antibiotic prevalence based on actual prescriptions and dosing patterns are insufficient.
Ramiro Sánchez-Huesca +3 more
doaj +3 more sources
Antimicrobial drug consumption in the Russian Federation (2008–2022): pharmacoepidemiological study [PDF]
Objective. To assess the dynamics of antimicrobial drug consumption in the Russian Federation. Materials and Methods. Data on antimicrobials for systemic use (ATC class J01) sales for the period 2008–2022 in the hospital and outpatient segment were ...
Gomon Yu.M. +7 more
doaj +1 more source
Background: The increase in antibiotic resistance is new developing threat to healthcare system. Irrational drug use, polypharmacy and the current epidemic of bacterial resistance is attributed to the increase in use of antibiotics.
doaj +2 more sources
Using defined daily doses to review antibiotic prescribing [PDF]
Optimising antibiotic prescribing in the primary care setting is a key component of the UK antimicrobial resistance (AMR) strategy. In this project, the authors worked with eight GP practices in Cornwall that had high levels of antibiotic prescribing to help them find ways to improve their prescribing and reduce antibiotic consumption, using defined ...
Marco Motta, Mike Wilcock, Adrian Heald
openaire +1 more source
Defined daily doses in pediatric dosing‐ a theoretical example
AbstractA defined daily dose for children (cDDD) taking body weight into account, was proposed as a better measure of drug utilization in children than the World Health Organization's DDD. There is no global definition of DDDs for children, and it is unclear which standard doses should be used for children when conducting drug utilization studies.
Elin Dahlén +2 more
openaire +3 more sources
Measuring drug exposure: concordance between defined daily dose and days' supply depended on drug class. [PDF]
Sinnott SJ +3 more
europepmc +2 more sources
Antimicrobial defined daily dose in neonatal population
Antimicrobial defined daily dose (DDD), a standardized metric to assess antimicrobial consumption in adult population, has limitations hampering its use in neonatal patients. This study proposes an alternative DDD design applicable for neonates.Neonates (
Villanueva-Bueno, Cristina +15 more
openaire +6 more sources
Penicillins’ defined daily doses must be changed [PDF]
Klein et al. (1) suggest that defined daily doses (DDDs) are not a perfect outcome measure of antibiotic prescribing, particularly for penicillins (39% of total DDDs in 2015 for broad-spectrum penicillins). We identified the same limitations as illustrated by the results of our study (2), which measured the bias of estimation for amoxicillin’s ...
Florent, Charra +2 more
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WHO defined daily doses versus hospital-adjusted defined daily doses: impact on results of antibiotic use surveillance [PDF]
To investigate effects on surveillance results of hospital antibiotic use when WHO defined daily doses (WHO DDDs) are adjusted to doses recommended for hospitalized patients [hospital-adjusted defined daily doses (haDDDs)].Data for antibiotic use in 2006-11 for all 22 Norwegian Health Enterprises were analysed with both WHO DDDs and haDDDs as ...
Jon Birger, Haug, Åsmund, Reikvam
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Fluoroquinolones: Utilisation and Compliance with WHO Defined Daily Doses [PDF]
Background: Fluoroquinolones are indicated for the treatment of a number of infections due to their broad-spectrum activity. Objectives: In the present study we aimed to describe the types and characteristics of fluoroquinolones prescribed, to examine the pattern of Fluoroquinolones used and to calculate and compare the Defined Daily Doses (DDD) for ...
Mohd Alfam Shamin Ashraf Alisha +8 more
openaire +1 more source

