Antimicrobial defined daily dose in neonatal population [PDF]
Antimicrobial defined daily dose (DDD), a standardized metric to assess antimicrobial consumption in adult population, has limitations hampering its use in neonatal patients. This study proposes an alternative DDD design applicable for neonates.Neonates (
Villanueva-Bueno, Cristina +15 more
openaire +6 more sources
Evaluation of Defined Daily Dose, percentage of British National Formulary maximum and chlorpromazine equivalents in antipsychotic drug utilization. [PDF]
ObjectiveThe present study was carried out to investigate and compare the three methods for calculating total antipsychotic dose among outpatients with schizophrenia attending primary psychiatric health care centers. The three methods were: Defined Daily
Sweileh WM +5 more
europepmc +3 more sources
Reforming the Swedish pharmaceuticals market: consequences for costs per defined daily dose [PDF]
In 2009 and 2010, the Swedish pharmaceuticals market was reformed. One of the stated policy goals was to achieve low costs for pharmaceutical products dispensed in Sweden. We use price and sales data for off-patent brand-name and generic pharmaceuticals to estimate a log-linear regression model, allowing us to assess how the policy changes affected the
Bergman, Mats +2 more
openaire +4 more sources
Background: The increase in antibiotic resistance is new developing threat to healthcare system. Irrational drug use, polypharmacy and the current epidemic of bacterial resistance is attributed to the increase in use of antibiotics.
doaj +2 more sources
Measuring drug exposure: concordance between defined daily dose and days' supply depended on drug class. [PDF]
Sinnott SJ +3 more
europepmc +2 more sources
Antimicrobial drug consumption in the Russian Federation (2008–2022): pharmacoepidemiological study [PDF]
Objective. To assess the dynamics of antimicrobial drug consumption in the Russian Federation. Materials and Methods. Data on antimicrobials for systemic use (ATC class J01) sales for the period 2008–2022 in the hospital and outpatient segment were ...
Gomon Yu.M. +7 more
doaj +1 more source
Sedative defined daily dose: suggestion for a new monitoring tool. [PDF]
Noritomi DT, Melo WP, Tavares MS.
europepmc +4 more sources
Defined daily doses in pediatric dosing‐ a theoretical example
AbstractA defined daily dose for children (cDDD) taking body weight into account, was proposed as a better measure of drug utilization in children than the World Health Organization's DDD. There is no global definition of DDDs for children, and it is unclear which standard doses should be used for children when conducting drug utilization studies.
Elin Dahlén +2 more
openaire +3 more sources
Using defined daily doses to review antibiotic prescribing [PDF]
Optimising antibiotic prescribing in the primary care setting is a key component of the UK antimicrobial resistance (AMR) strategy. In this project, the authors worked with eight GP practices in Cornwall that had high levels of antibiotic prescribing to help them find ways to improve their prescribing and reduce antibiotic consumption, using defined ...
Marco Motta, Mike Wilcock, Adrian Heald
openaire +1 more source
Penicillins’ defined daily doses must be changed [PDF]
Klein et al. (1) suggest that defined daily doses (DDDs) are not a perfect outcome measure of antibiotic prescribing, particularly for penicillins (39% of total DDDs in 2015 for broad-spectrum penicillins). We identified the same limitations as illustrated by the results of our study (2), which measured the bias of estimation for amoxicillin’s ...
Florent, Charra +2 more
openaire +2 more sources

