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Discrepancies between prescribed daily doses and WHO defined daily doses of antibacterials at a university hospital [PDF]
British Journal of Clinical Pharmacology, 2006 Aims The defined daily doses (DDD) defined by the WHO are widely used as an indicator to measure antibiotic use in the hospital setting. However, discrepancies exist between countries in terms of antibiotic dosage. The aim of the present study was to compare, for each antibacterial agent available at our university hospital, the prescribed daily doses (
Xavier Bertrand +2 more
exaly +5 more sources
Assessment of postoperative changes in antihypertensive drug consumption in patients with primary aldosteronism using the defined daily dose [PDF]
Asian Journal of Surgery, 2014 SummaryBackgroundThe number of antihypertensive drug classes cannot accurately reflect the total consumption of antihypertensive drugs used to control blood pressure.
Hidekazu Nagano +2 more
exaly +2 more sources
Coping with changes in the Defined Daily Dose in a longitudinal drug consumption database [PDF]
Pharmacy World & Science, 2010 To illustrate the best approach to accurate representation of temporal evolution of drug consumption, when confronted with changes over time in the Defined Daily Dose (DDD) measurement unit.As an example, drug consumption (2001-2005) at the University Hospital Rijeka was expressed with the corresponding DDD in each year; and with the DDD value of the ...
Vlahović-Palčevski, Vera +4 more
openaire +3 more sources
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Applying “Children Defined Daily Dose” to assess appropriate dose in pediatrics
Journal of Evidence-Based Medicine, 2012Abstract Objective: Inappropriate drug dosage is a serious problem in pediatrics, mainly due to the lack of clinical evidence in children, suitable preparation formulation, and standardized methods for dose adjustment. A method for evaluating and monitoring appropriate dosage in pediatrics is urgently needed.
Lingli, Zhang +3 more
openaire +2 more sources
Chlorpromazine Equivalents Versus Defined Daily Doses: How to Compare Antipsychotic Drug Doses?
Journal of Clinical Psychopharmacology, 2003Classic chlorpromazine (CPZ) equivalents can be used to chart relative antipsychotic potencies of antipsychotic drugs. Values of CPZ equivalents per drug are ambiguous in literature. In drug use evaluation studies, antipsychotic doses are frequently compared by use of the defined daily dose (DDD). The DDD is the assumed average maintenance dose per day
Rijcken, C. A. W. +3 more
openaire +2 more sources
International Journal of Clinical Pharmacy, 2017
Background Although defined daily doses (DDD) for antiepileptic drugs (AED) have been assigned only in combination therapy, based on the literature, most patients take them in monotherapy. Furthermore, discrepancies between DDD and prescribed daily dose (PDD) were observed.
László Horváth +3 more
openaire +2 more sources
Background Although defined daily doses (DDD) for antiepileptic drugs (AED) have been assigned only in combination therapy, based on the literature, most patients take them in monotherapy. Furthermore, discrepancies between DDD and prescribed daily dose (PDD) were observed.
László Horváth +3 more
openaire +2 more sources
Hospital statistics for antibiotics: defined versus prescribed daily dose
Infection, 2014Defined daily doses (DDD) are widely used as a unit to measure drug use in hospital and community settings. However, discrepancies exist between DDD and actual prescribed daily dose (PDD). The present study aims at estimating an alternative PDD (PDD-proxy) to calculate rates of systemic antibiotic consumption and to compare these results with those ...
C, Gagliotti +5 more
openaire +2 more sources