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Chlorpromazine Equivalents Versus Defined Daily Doses: How to Compare Antipsychotic Drug Doses?
Journal of Clinical Psychopharmacology, 2003Classic chlorpromazine (CPZ) equivalents can be used to chart relative antipsychotic potencies of antipsychotic drugs. Values of CPZ equivalents per drug are ambiguous in literature. In drug use evaluation studies, antipsychotic doses are frequently compared by use of the defined daily dose (DDD). The DDD is the assumed average maintenance dose per day
Rijcken, C. A. W. +3 more
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Applying “Children Defined Daily Dose” to assess appropriate dose in pediatrics
Journal of Evidence-Based Medicine, 2012Abstract Objective: Inappropriate drug dosage is a serious problem in pediatrics, mainly due to the lack of clinical evidence in children, suitable preparation formulation, and standardized methods for dose adjustment. A method for evaluating and monitoring appropriate dosage in pediatrics is urgently needed.
Lingli, Zhang +3 more
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International Journal of Clinical Pharmacy, 2017
Background Although defined daily doses (DDD) for antiepileptic drugs (AED) have been assigned only in combination therapy, based on the literature, most patients take them in monotherapy. Furthermore, discrepancies between DDD and prescribed daily dose (PDD) were observed.
László Horváth +3 more
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Background Although defined daily doses (DDD) for antiepileptic drugs (AED) have been assigned only in combination therapy, based on the literature, most patients take them in monotherapy. Furthermore, discrepancies between DDD and prescribed daily dose (PDD) were observed.
László Horváth +3 more
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Hospital statistics for antibiotics: defined versus prescribed daily dose
Infection, 2014Defined daily doses (DDD) are widely used as a unit to measure drug use in hospital and community settings. However, discrepancies exist between DDD and actual prescribed daily dose (PDD). The present study aims at estimating an alternative PDD (PDD-proxy) to calculate rates of systemic antibiotic consumption and to compare these results with those ...
C, Gagliotti +5 more
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Verschillen tussen WHO ‘Defined Daily Doses’ en ‘Prescribed Daily Doses’ van antibiotica
Medisch-Farmaceutische Mededelingen, 2006Op Europees niveau wordt veel onderzoek gedaan naar antibioticagebruik, zowel extra- als intramuraal 1,2. Voor het uitdrukken van blootstelling aan antibiotica wordt in het algemeen de ATC/DDD-methodologie van de WHO gebruikt. Hierbij wordt het aantal ‘defined daily doses’ (DDD’s) gedefinieerd als ‘de aangenomen gemiddelde onderhoudsdosering per dag ...
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Coping with changes in the Defined Daily Dose in a longitudinal drug consumption database [PDF]
Pharmacy World & Science, 2010 To illustrate the best approach to accurate representation of temporal evolution of drug consumption, when confronted with changes over time in the Defined Daily Dose (DDD) measurement unit.As an example, drug consumption (2001-2005) at the University Hospital Rijeka was expressed with the corresponding DDD in each year; and with the DDD value of the ...
Vlahović-Palčevski, Vera +4 more
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Data Fusion to Convert Drug Consumption Quantities into Defined Daily Doses
2020Analysis of consumptions has proved a misuse of antibiotics, despite the existence of national requirements. To be able to compute drugs consumption quantities of highly heterogeneous drugs expressed in various doses units, the World Health Organization has defined a defined daily dose.
Ugon, Adrien +2 more
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