A Drug Utilization Evaluation of Bronchodilators Using a Defined Daily Dose Method
Drug therapy is crucial to promoting human health by increasing quality of life and extending lifespan. A method to assess and improve drug use is by conducting Drug Utilization Study. Drug utilization, in terms of DDD, aids in converting the available volume of medications into medically relevant units, allowing estimations of the number of people ...
Afreen Nasir - +2 more
openaire +1 more source
Background: Antimicrobial consumption (AMC) data in Latin America are scarce and usually spread out across different sources used to make AMC calculations, making it difficult to both standardize and compare regions through similar time frames.
Cristina Fernández-Barrantes +6 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
High dose rate brachytherapy as monotherapy for localised prostate cancer : a hypofractionated two-implant approach in 351 consecutive patients [PDF]
BACKGROUND: To report the clinical outcome of high dose rate brachytherapy as sole treatment for clinically localised prostate cancer. METHODS: Between March 2004 and January 2008, a total of 351 consecutive patients with clinically localised prostate ...
Markus Ratka +13 more
core +1 more source
Developing Canadian Defined Daily Doses for Animals: A Metric to Quantify Antimicrobial Use [PDF]
Antimicrobial use surveillance data need to be analyzed and reported in a standardized and harmonized way. In veterinary medicine, one approach is to use defined daily doses (DDD) for animals. DDD for animals are technical standards used in various measures or metrics that quantify antimicrobial use.
Angelina L. Bosman +6 more
openaire +3 more sources
Trends and characteristics of pethidine use in Taiwan: a six-year-long survey
OBJECTIVES: To investigate the trends and characteristics of pethidine prescriptions and users in Taiwan from 2002 to 2007. METHOD: All pethidine users (n = 3,301,136) in Taiwan from 2002 to 2007 were linked to National Health Insurance claims to ...
Hsueh-Hsing Pan +5 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
ON THE AUTOMORPHISMS OF THE NONSPLIT CARTAN MODULAR CURVES OF PRIME LEVEL [PDF]
We study the automorphisms of the nonsplit Cartan modular curves Xns(p) of prime level p. We prove that if p ≥ 29 all the automorphisms preserve the cusps.
VALERIO DOSE, Dose V.
core +1 more source
A survey of antibiotics dispensing pattern in a community pharmacy of Pune city
Background: A community pharmacist is generally involved in the activities such as dispensing of drugs and medication aids, billing, patient counseling, and provision of pharmaceutical care.
Akshay V Mule +3 more
doaj +1 more source

