Results 91 to 100 of about 7,998,479 (274)

Establishing consensus on the definition of an isolated hip fracture for trauma system performance evaluation: A systematic review

open access: yesJournal of Emergencies, Trauma and Shock, 2014
Background: Risk-adjusted mortality is widely used to benchmark trauma center care. Patients presenting with isolated hip fractures (IHFs) are usually excluded from these evaluations. However, there is no standardized definition of an IHF.
Judith Tiao   +3 more
doaj   +1 more source

Definitions of resilience and resilience resource use as described by adults with congenital heart disease

open access: gold, 2023
Jill M. Steiner   +7 more
openalex   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Event Data Definition in LHCb

open access: yes, 2003
We present the approach used for defining the event object model for the LHCb experiment. This approach is based on a high level modelling language, which is independent of the programming language used in the current implementation of the event data ...
Cattaneo, Marco   +5 more
core   +1 more source

Defining mesenchymal stromal cell (MSC)-derived small extracellular vesicles for therapeutic applications

open access: yesJournal of Extracellular Vesicles, 2019
Small extracellular vesicles (sEVs) from mesenchymal stromal/stem cells (MSCs) are transiting rapidly towards clinical applications. However, discrepancies and controversies about the biology, functions, and potency of MSC-sEVs have arisen due to several
Kenneth W. Witwer   +18 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

An Operational Definition of Topological Order

open access: yes, 2020
The unrivaled robustness of topologically ordered states of matter against perturbations has immediate applications in quantum computing and quantum metrology, yet their very existence poses a challenge to our understanding of phase transitions.
Jamadagni, Amit, Weimer, Hendrik
core  

Who are „Young Carers”? Analysis of the Use of the Term in German Speaking Countries and Development of a Definition / Wer sind Young Carers? Analyse der Begriffsverwendung im deutschsprachigen Raum und Entwicklung einer Definition

open access: yesInternational Journal of Health Professions, 2019
Children and adolescents with caring responsibility who are looking after a family member or a person close are often hiding from the view of the public.
Frech Marianne   +5 more
doaj   +1 more source

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