Results 51 to 60 of about 1,222 (128)

TRIM: Simultaneous Thermometry, Ranging, and Imaging via a Monolithic Metalens

Advanced Science, EarlyView.
ABSTRACT While metasurfaces offer a pathway beyond the discrete architectures of conventional LWIR systems, physically fusing high‐precision thermometry and passive ranging onto a single metalens remains a formidable challenge. Here, we demonstrate a monolithic, dual‐focus metalens capable of simultaneous multidimensional sensing.
Man Yuan, Yuqing Zhang, Wangzhe Zhou, Zhaojian Zhang, Xiaoyun He, Xinpeng Jiang, Yiyi Li, Xin He, Jiagui Wu, Yuanmu Yang, Junbo Yang   +10 more
wiley   +1 more source

Evaluation of the peripheral visual performance of DIMS spectacle lenses versus single vision lenses

Frontiers in Neuroscience
PurposeThis study evaluates differences in the visual field performance when wearing the Defocus Incorporated Multiple Segments (DIMS) spectacle lens compared to wearing a conventional single vision (SV) spectacle lens.MethodsTwenty-one children aged 9 ...
Kenneth Ka King Liu, Kenneth Ka King Liu, Kenneth Ka King Liu, Kenneth Ka King Liu, Han Yu Zhang, Han Yu Zhang, Han Yu Zhang, Daisy Ka Yan Leung, Daisy Ka Yan Leung, Daisy Ka Yan Leung, Carly Siu Yin Lam, Carly Siu Yin Lam, Carly Siu Yin Lam, Carly Siu Yin Lam   +13 more
doaj   +1 more source

Allosteric Inhibition of Polycomb Repressive Complex 2 by an EZH2‐Selective Small Molecule Inhibitor

Advanced Science, EarlyView.
The study characterizes C36, a highly selective EZH2/PRC2 inhibitor that acts via a novel allosteric mechanism. Unlike previous inhibitors, C36 inhibits EZH2/PRC2 by disrupting the allosteric communication between EZH2 and EED in a SAM‐noncompetitive manner.
Ting Cao, Dongdong Liu, Haishan Gao, Chenyang Qin, Wen Zhang, Ziyun Lu, Dongxia Tan, Yuxiu Qu, Yusong Liu, Zhiran Zou, Hongtao Yu, Wei Qi   +11 more
wiley   +1 more source

Long-term myopia control effect and safety in children wearing DIMS spectacle lenses for 6 years

Scientific Reports, 2023
This study evaluated the long-term myopia control effect and safety in children wearing Defocus Incorporated Multiple Segments (DIMS) spectacle lenses.
Carly Siu Yin Lam, Wing Chun Tang, Han Yu Zhang, Paul H. Lee, Dennis Yan Yin Tse, Hua Qi, Natalia Vlasak, Chi Ho To   +7 more
doaj   +1 more source

Effects of atropine, orthokeratology lenses, defocus contact lenses, and Defocus Incorporated Multiple Segments spectacle lenses on choroidal thickness

Journal of the Formosan Medical Association
This study aimed to compare the effects of various myopia control methods, including atropine, orthokeratology (OK) lenses, defocus soft contact lenses (MiSight®, MS), and defocus incorporated multiple segment spectacle lenses (Hyoa Miyosmart®, HY), on choroidal thickness in children with myopia.This single-center, retrospective study was conducted at ...
Hou-Ting Kuo, Hsin Tseng, Yu-Chuen Huang, Yu-Te Huang, Hui-Ju Lin   +4 more
openaire   +2 more sources

Conformational Snapshots of CydDC in a Native Lipid Bilayer Coupling Heme Transport to Antibiotic Resistance

Advanced Science, EarlyView.
Phylogenetic and biochemical analyses of the heme transporter CydDC reveal its functional conservation throughout bacterial evolution and demonstrate its unique asymmetric allosteric mechanism. Furthermore, impairment of CydDC function directly affects bacterial antibiotic resistance and likely compromises antibiotic efficacy through drug efflux.
Lili Yang, Changbin Zhang, Mengyuan Lyu, Yongbo Luo, Jierou Zhang, Yujiao Chen, Lintao Luo, Wen Qiao, Xiangyangpeng Li, Yu Zhou, Zhongling Wei, Yuling Xiao, Qian Niu, Juan Zhou, Guanglin He, Binwu Ying, Zhaoming Su, Hao Chen, Xiaodi Tang, Haohao Dong   +19 more
wiley   +1 more source

Reduced myopia progression with low-dose atropine in DIMS non-responders and evidence of altered pupillary light reflex kinetics

Scientific Reports
This study evaluated the efficacy of adding nightly 0.025% atropine to Defocus Incorporated Multiple Segments (DIMS) spectacle treatment in children with ongoing myopia progression and explored whether dynamic pupillometry could help identify such ...
Patricia Domsa, Attila Törcsvári, Viktória Baross, Judit Körtvélyes, Rita Széchey, Adrienne Csutak, Éva M Bankó   +6 more
doaj   +1 more source

Hardware‐Attentive Programmable Fourier Ptychography Enables Task‐Adaptive Label‐Free Virtual Staining

Advanced Science, EarlyView.
Task‐adaptive programmable optics enables label‐free virtual staining through optical‐attention‐guided acquisition and reconstruction. By optimizing wavelength, illumination angle, exposure time, and imaging depth, the framework learns task‐relevant optical measurements, generating clinically interpretable virtual stains with improved fidelity, non ...
Tianyue He, Wenyi Jing, Le Zhang, Qican Zhang, Tingdong Kou, Xin He, Yan Qiu, Yang Lu, Jian Cui, Yongfu Wen, Zhenrong Zheng, Hongying Zhang, Dayong Jin, Junfei Shen   +13 more
wiley   +1 more source

Myopia control: short-term effect of 0.01% atropine vs. defocus incorporated multiple segment lenses—a retrospective study in European children

International Ophthalmology, 2023
Abstract Purpose To compare 0.01% atropine with DIMS spectacle lenses in the prevention of myopia progression in European children. Methods This was a retrospective study including data from pediatric European patients with myopia. From November 2021 to March 2022, only 0.01%
Sandra Guimarães, Patrícia Barros da Silva, Bárbara Oliveiros, Eduardo Silva   +3 more
openaire   +3 more sources

MAM‐Localized MANF Counteracts Microinflammatory Stress to Attenuate Mitochondrial Dysfunction and Cataractogenesis in High Myopia

Advanced Science, EarlyView.
Chronic microinflammation in high myopia suppresses MANF in lens epithelial cells. MANF normally resides within MAMs and promotes ubiquitin‐mediated degradation of the ER Ca2+ pump SERCA2. MANF loss causes pathological SERCA2 accumulation, MAM hyperassembly, and disrupted ER‐to‐mitochondria Ca2+ transfer, leading to mitochondrial failure, oxidative ...
Xin Liu, Hao Li, Ching Kang, Dongling Guo, Shuyu Liu, Jiaqi Meng, Zhiqian Huang, Yu Du, Xiangjia Zhu   +8 more
wiley   +1 more source