Results 31 to 40 of about 5,241 (151)

Network structure of brain atrophy in de novo Parkinson's disease

eLife, 2015
We mapped the distribution of atrophy in Parkinson's disease (PD) using magnetic resonance imaging (MRI) and clinical data from 232 PD patients and 117 controls from the Parkinson's Progression Markers Initiative.
Yashar Zeighami, Miguel Ulla, Yasser Iturria-Medina, Mahsa Dadar, Yu Zhang, Kevin Michel-Herve Larcher, Vladimir Fonov, Alan C Evans, D Louis Collins, Alain Dagher   +9 more
doaj   +1 more source

Brain Atrophy and Reorganization of Structural Network in Parkinson's Disease With Hemiparkinsonism

Frontiers in Human Neuroscience, 2018
Hemiparkinsonism duration in patients with Parkinson's disease (PD) is a key time window to study early pathology of PD. We aimed to comprehensively explore the alterations of deformation and structural network in PD patients with hemiparkinsonism, which
Xiaojun Xu, Xiaojun Guan, Tao Guo, Qiaoling Zeng, Rong Ye, Jiaqiu Wang, Jianguo Zhong, Min Xuan, Quanquan Gu, Peiyu Huang, Jiali Pu, Baorong Zhang, Minming Zhang   +12 more
doaj   +1 more source

Statistical techniques for predicting rupture risk in abdominal aortic aneurysms: A contribution based on bootstrap

Science Progress, 2021
The morphometry of abdominal aortic aneurysms (AAA) has been recognized as one of the main factors that may predispose them to rupture. The need to quantify the morphometry of AAA on a patient-specific basis constitutes a valuable tool for assisting in ...
Félix Nieto-Palomo, María-Ángeles Pérez-Rueda, Laurentiu-Mihai Lipsa, Carlos Vaquero-Puerta, José-Alberto Vilalta-Alonso, Guillermo Vilalta-Alonso, Eduardo Soudah-Prieto   +6 more
doaj   +1 more source

Deformation-Based Morphometry and Its Relation to Conventional Volumetry of Brain Lateral Ventricles in MRI [PDF]

NeuroImage, 2001
Deformation-based morphometry (DBM) is a useful technique to detect morphological differences over the entire brain since it analyses positional differences between every voxel and a standard brain. In this report we compare DBM to semimanual tracing of brain ventricles in a population of 39 patients with schizophrenia.
C, Gaser, I, Nenadic, B R, Buchsbaum, E A, Hazlett, M S, Buchsbaum   +4 more
openaire   +2 more sources

DeepAtrophy: Teaching a neural network to detect progressive changes in longitudinal MRI of the hippocampal region in Alzheimer's disease

NeuroImage, 2021
Measures of change in hippocampal volume derived from longitudinal MRI are a well-studied biomarker of disease progression in Alzheimer's disease (AD) and are used in clinical trials to track therapeutic efficacy of disease-modifying treatments. However,
Mengjin Dong, Long Xie, Sandhitsu R. Das, Jiancong Wang, Laura E.M. Wisse, Robin deFlores, David A. Wolk, Paul A. Yushkevich   +7 more
doaj   +1 more source

Assessment of brain growth in early childhood using deformation-based morphometry

NeuroImage, 2008
We present methods for the quantitative analysis of brain growth based on the registration of longitudinal MR image data with the use of Jacobian determinant maps to characterise neuroanatomical changes. The individual anatomies, growth maps and tissue classes are also spatially normalised in an 'average space' and aggregated to provide atlases for the
Paul Aljabar, Kanwal K. Bhatia, Maria Murgasova, Joseph V. Hajnal, James P. Boardman, Latha Srinivasan, Mary A. Rutherford, Leigh Dyet, A. David Edwards, Daniel Rueckert   +9 more
openaire   +3 more sources

Early changes in brain structure correlate with language outcomes in children with neonatal encephalopathy

NeuroImage: Clinical, 2017
Global patterns of brain injury correlate with motor, cognitive, and language outcomes in survivors of neonatal encephalopathy (NE). However, it is still unclear whether local changes in brain structure predict specific deficits.
Kevin A. Shapiro, Hosung Kim, Maria Luisa Mandelli, Elizabeth E. Rogers, Dawn Gano, Donna M. Ferriero, A. James Barkovich, Maria Luisa Gorno-Tempini, Hannah C. Glass, Duan Xu   +9 more
doaj   +1 more source

Volumetric brain correlates of gait associated with cognitive decline in community-dwelling older adults

Frontiers in Aging Neuroscience, 2023
ObjectiveTo determine the extent to which the regional brain volumes associated with slow gait speed can inform subsequent cognitive decline in older adults from the Rush Memory and Aging Project.ApproachWe utilized deformation-based morphometry (DBM) in
Victoria N. Poole, Victoria N. Poole, Shahram Oveisgharan, Shahram Oveisgharan, Lei Yu, Lei Yu, Robert J. Dawe, Robert J. Dawe, Sue E. Leurgans, Sue E. Leurgans, Sue E. Leurgans, Shengwei Zhang, Konstantinos Arfanakis, Konstantinos Arfanakis, Aron S. Buchman, Aron S. Buchman, David A. Bennett, David A. Bennett   +17 more
doaj   +1 more source

Applying surface-based hippocampal morphometry to study APOE-E4 allele dose effects in cognitively unimpaired subjects

NeuroImage: Clinical, 2019
Apolipoprotein E (APOE) e4 is the major genetic risk factor for late-onset Alzheimer's disease (AD). The dose-dependent impact of this allele on hippocampal volumes has been documented, but its influence on general hippocampal morphology in cognitively ...
Qunxi Dong, Wen Zhang, Jianfeng Wu, Bolun Li, Emily H. Schron, Travis McMahon, Jie Shi, Boris A. Gutman, Kewei Chen, Leslie C. Baxter, Paul M. Thompson, Eric M. Reiman, Richard J. Caselli, Yalin Wang   +13 more
doaj   +1 more source

Applying surface-based morphometry to study ventricular abnormalities of cognitively unimpaired subjects prior to clinically significant memory decline

NeuroImage: Clinical, 2020
Ventricular volume (VV) is a widely used structural magnetic resonance imaging (MRI) biomarker in Alzheimer’s disease (AD) research. Abnormal enlargements of VV can be detected before clinically significant memory decline.
Qunxi Dong, Wen Zhang, Cynthia M. Stonnington, Jianfeng Wu, Boris A. Gutman, Kewei Chen, Yi Su, Leslie C. Baxter, Paul M. Thompson, Eric M. Reiman, Richard J. Caselli, Yalin Wang   +11 more
doaj   +1 more source