Deformation-based Morphometry MRI Reveals Brain Structural Modifications in Living Mu Opioid Receptor Knockout Mice [PDF]
Mu opioid receptor (MOR) activation facilitates reward processing and reduces pain, and brain networks underlying these effects are under intense investigation.
Md Taufiq Nasseef +9 more
doaj +2 more sources
Deformation-based morphometry of prospective neurodevelopmental changes in new onset paediatric epilepsy. [PDF]
Epilepsy is a prevalent childhood neurological disorder, but there are few prospective quantitative magnetic resonance imaging studies examining patterns of brain development compared to healthy controls. Controlled prospective investigations initiated at or near epilepsy onset would best characterize the nature, timing and course of neuroimaging ...
Tosun D +6 more
europepmc +4 more sources
Exploring the Morphological Study of the Brain in Patients with Bipolar Disorder Based on Structural Magnetic Resonance Imaging [PDF]
Jiayue Chen,1,2,* Hongjun Tian,2,* Xinxin Zhang,3,* Yingchao Song,4 Yanmin Peng,5 Guotao Yin,6 Qianchen Li,7 Xiaoxiao Xiao,5 Yu Zhang,8 Jun Chen,1 Chuanjun Zhuo9 1Clinical Research Center, Shanghai Mental Health Center, Shanghai ...
Chen J +10 more
doaj +2 more sources
Data-driven subtyping and staging of ALS: A multicenter, longitudinal, deformation-based morphometry study. [PDF]
Abstract Amyotrophic lateral sclerosis (ALS) is clinically and biologically heterogeneous, yet data-driven imaging subtyping approaches have rarely been validated longitudinally or linked to clinical and survival outcomes. We aimed to identify and validate distinct ALS subtypes and disease stages using deformation-based morphometry (DBM)
Lajoie I, Kalra S, Dadar M.
europepmc +2 more sources
Deformation-based morphometry of brain changes in alcohol dependence and abstinence. [PDF]
Brain atrophy associated with chronic alcohol consumption is partially reversible after cessation of drinking. Recovering alcoholics (RA, 45+/-8 years) were studied with MRI within 1 week of entering treatment, with follow-up at 8 months. Light drinkers (LD) were studied with MRI twice 1 year apart.
Cardenas VA +4 more
europepmc +4 more sources
Deformation-based brain morphometry in rats
Magnetic resonance imaging (MRI)-based morphometry provides in vivo evidence for macro-structural plasticity of the brain. Experiments on small animals using automated morphometric methods usually require expensive measurements with ultra-high field dedicated animal MRI systems.
Jürgen R Reichenbach +2 more
exaly +3 more sources
Amygdalar and Hippocampal Morphometry Abnormalities in First-Episode Schizophrenia Using Deformation-Based Shape Analysis [PDF]
In this study, we investigated and quantified the amygdalar and hippocampal morphometry abnormalities exerted by first-episode schizophrenia using a total of 92 patients and 106 healthy control participants.
Xiaoying Tang +5 more
doaj +3 more sources
Longitudinal deformation-based morphometry reveals spatio-temporal dynamics of brain volume changes in patients with corticobasal syndrome. [PDF]
BACKGROUND/OBJECTIVE: Corticobasal syndrome (CBS) is a rare neurodegenerative disorder characterized by a progressive and asymmetric manifestation of cortical and basal-ganglia symptoms of different origin.
Martin Südmeyer +10 more
doaj +2 more sources
A 3D‐Printed Blister Test Platform for Quantifying Biointerface Adhesion Mechanisms
Engineering robust soft–rigid interfaces remains a central challenge in functional materials, limiting the durability of hydrogel‐based implants, biointegrated systems, and hybrid composites.
Yoontae Kim +4 more
doaj +2 more sources
Preterm birth is a leading risk factor for neurodevelopmental and cognitive impairment in childhood and adolescence. The most common known cerebral abnormality among preterm infants at term equivalent age is a diffuse white matter abnormality seen on magnetic resonance (MR) images.
Joseph Hajnal +2 more
exaly +4 more sources

