Results 61 to 70 of about 1,629,828 (298)

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

Crustal deformation

open access: yesEos, Transactions American Geophysical Union, 1991
One of the lessons of geology, and now one of the tenets of plate tectonics theory, is that most of the Earth's crust does not deform very much. Most of the deformation takes place along the relatively narrow plate boundaries. Working out the details of how this deformation takes place, and the physics of the Earth revealed by it, is a major research ...
openaire   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Deformation quantization modules [PDF]

open access: yes, 2011
We study modules over stacks of deformation quantization algebroids on complex Poisson manifolds. We prove finiteness and duality theorems in the relative case and construct the Hochschild class of coherent modules. We prove that this class commutes with
Kashiwara, Masaki, Schapira, Pierre
core   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

Strategic niobium integration and thermomechanical processing in the advancement of novel CMnSiAlPMo TRIP-aided bainitic steel

open access: yesScientific Reports
This study examines the effects of niobium (Nb) addition and different thermomechanical controlled processing (TMCP) regimes on the flow stress behaviour and microstructure evolution of a newly developed CMnSiAlPMo TRIP-aided bainitic steel.
Hoda Refaiy   +3 more
doaj   +1 more source

Using GPS as a reference frame for SAR images applied to a post eruptive period for Okmok Volcano, Aleutian Islands, Alaska [PDF]

open access: yes, 2012
While high spatial coverage makes InSAR a popular tool to study active volcanoes its use can possess challenges for certain environments. Volcanoes along Alaska's Aleutian chain are difficult targets for InSAR as their seasonal snow cover causes ...
Miller, Summer A.
core  

Rate dependent shear bands in a shear transformation zone model of amorphous solids [PDF]

open access: yes, 2008
We use Shear Transformation Zone (STZ) theory to develop a deformation map for amorphous solids as a function of the imposed shear rate and initial material preparation.
D. Griggs   +5 more
core   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Infinitesimal deformations of a formal symplectic groupoid

open access: yes, 2011
Given a formal symplectic groupoid $G$ over a Poisson manifold $(M, \pi_0)$, we define a new object, an infinitesimal deformation of $G$, which can be thought of as a formal symplectic groupoid over the manifold $M$ equipped with an infinitesimal ...
A. Karabegov   +15 more
core   +1 more source

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