Results 41 to 50 of about 485,129 (264)

Deformed defects [PDF]

Physical Review D, 2002
We introduce a method to obtain deformed defects starting from a given scalar field theory which possesses defect solutions. The procedure allows the construction of infinitely many new theories that support defect solutions, analytically expressed in terms of the defects of the original theory. The method is general, valid for both topological and non-
Bazeia, D., Losano, L., Malbouisson, J. M. C.   +2 more
openaire   +2 more sources

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Tectonic-structural systems of Mars: Is it possible to use them to reconstruct its thermal evolution? [PDF]

Geofísica Internacional, 2004
This work tries to establish the possible relationship among cortical stresses evidenced by faults mapped in the surface and thermal evolution on Mars.
J. F. Valdés-Galicia, Antonio H. Barosio   +1 more
doaj  

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Deformations of Calabi-Yau hypersurfaces arising from deformations of toric varieties

, 2003
There are easy "polynomial" deformations of Calabi-Yau hypersurfaces in toric varieties performed by changing the coefficients of the defining polynomial of the hypersurface. In this paper, we explicitly constructed the ``non-polynomial'' deformations of
Altmann, Anvar R. Mavlyutov, Batyrev, Batyrev, Candelas, Cox, Danilov, Demazure, Katz, Mavlyutov, Mavlyutov, Mavlyutov, Ran, Todorov   +13 more
core   +2 more sources

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Quantum deformations of associative algebras and integrable systems

, 2008
Quantum deformations of the structure constants for a class of associative noncommutative algebras are studied. It is shown that these deformations are governed by the quantum central systems which has a geometrical meaning of vanishing Riemann curvature
Ablowitz M J, B G Konopelchenko, Casati P Falqui G Magri F Pedroni M, Coates T, Dirac P A M, Dubrovin B, Dubrovin B, Eisenhart L P, Eliashberg Y, Givental A, Givental A, Hertling C, Hertling C, Kito H, Konopelchenko B G, Konopelchenko B G Magri F, Losev A, Manin Y I, Nomizu K, Novikov S P, Whitham G B, Willmore T J, Zakharov V E   +22 more
core   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source