Results 111 to 120 of about 57,363 (292)
Figure 6-Association complexity degeneracy
, 2011 Association between complexity and degeneracy for evolved genetic networks with and without feedback ...
Elena, Santiago F. +5 more
core +1 more source
Exaptation and emerging degeneracy in innovation processes [PDF]
, 2013 In socio-economic innovation processes, exaptations emerge from processes through which an initial attribution of new functionalities to existing artifacts or organizations leads to new artifacts and eventually to new markets. In this paper, I argue that
BONIFATI, Giovanni
core +1 more source
Morphogenetic degeneracies in the actomyosin cortex
eLife, 2018 One of the great challenges in biology is to understand the mechanisms by which morphogenetic processes arise from molecular activities. We investigated this problem in the context of actomyosin-based cortical flow in C.
Sundar Ram Naganathan +7 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem +9 more
wiley +1 more source
Stage‐Dependent β‐Synuclein Links MRI and Cognitive Decline in Alzheimer's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Synaptic degeneration drives cognitive decline in Alzheimer's disease (AD), but synaptic biomarkers are scarce. Brain‐enriched β‐synuclein emerged as a synaptic damage marker. We investigated its diagnostic, prognostic, and structural correlates across the AD continuum.
Ulaş Ay +15 more
wiley +1 more source
Degeneracy and parity states of fractional quantum mechanics in infinite square well
四川大学学报. 自然科学版This paper aims at the fractional quantum mechanics in infinite square well.The wave functions of a particle in an infinitely square well is obtained by solving the corresponding fractional Schrödinger equation， the degeneracy and parity states of the ...
DUAN Xueling +3 more
doaj
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a clinically heterogeneous neurodegenerative disease requiring reliable biomarkers to improve patient stratification and trial design. While serum neurofilament light chain (sNfL) reflects neuroaxonal stress and disease aggressiveness, troponin T (TnT) may capture complementary aspects of ...
Julia Sellin +8 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Progressive brain atrophy has now been widely observed in the chronic stages of moderate–severe traumatic brain injury (msTBI), but there is only coarse information regarding its prevalence and magnitude, and whether rate of atrophy accelerates or attenuates across time. We examined these questions in a Canadian inception cohort from
Robin E. A. Green +6 more
wiley +1 more source
Degeneracy in discrete infinite horizon optimization.
, 1988 Infinite horizon sequential decision problems may be solved by identifying a solution horizon, a finite time horizon that is long enough to yield an optimal initial decision for the infinite horizon problem.
Ryan, Sarah McAllister
core +4 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Neuromyelitis optica spectrum disorder (NMOSD) is a devastating neurological disease that lacks serological biomarkers that can accurately reflect disease activity. We established a live cell‐based assay (LCBA) using serum with endogenous complement to quantify the overall cytotoxicity, offering a novel functional tool for monitoring
Xiaona Xu +10 more
wiley +1 more source