Results 1 to 10 of about 36,148 (305)

Neuronal oscillations enhance stimulus discrimination by ensuring action potential precision.

open access: yesPLoS Biology, 2006
Although oscillations in membrane potential are a prominent feature of sensory, motor, and cognitive function, their precise role in signal processing remains elusive.
Andreas T Schaefer   +3 more
doaj   +2 more sources

The effects of membrane potential oscillations on the excitability of rat hypoglossal motoneurons

open access: yesFrontiers in Physiology, 2022
Oscillations in membrane potential induced by synaptic inputs and intrinsic ion channel activity play a role in regulating neuronal excitability, but the precise mechanisms underlying their contributions remain largely unknown.
Qiang Zhang   +7 more
doaj   +3 more sources

An agent-based model of metabolic signaling oscillations in Bacillus subtilis biofilms. [PDF]

open access: yesPLoS Computational Biology
Microbes of nearly every species can form biofilms, communities of cells bound together by a self-produced matrix. It is not understood how variation at the cellular level impacts putatively beneficial, colony-level behaviors, such as cell-to-cell ...
Obadiah J Mulder   +4 more
doaj   +2 more sources

Variable mechanisms of action of lithium during generating of membrane potential oscilations across the excitable membrane of the Nitela cell [PDF]

open access: yesZbornik Matice Srpske za Prirodne Nauke, 2012
This study presents results on variable mechanisms of lithium transport processes during generating of membrane potential oscillations across the very excitable membrane of the Nittela cell.
Radenović Čedomir N.   +3 more
doaj   +1 more source

Sodium-mediated plateau potentials in an identified decisional neuron contribute to feeding-related motor pattern genesis in Aplysia

open access: yesFrontiers in Neural Circuits, 2023
Motivated behaviors such as feeding depend on the functional properties of decision neurons to provide the flexibility required for behavioral adaptation.
Alexis Bédécarrats   +2 more
doaj   +1 more source

The mitochondrial membrane potential and Ca2+ oscillations in smooth muscle [PDF]

open access: yesJournal of Cell Science, 2008
Ca2+ uptake by mitochondria might both modulate the cytosolic Ca2+ concentration ([Ca2+]c) and depolarize the mitochondrial membrane potential (ΔΨm) to limit ATP production. To investigate how physiological Ca2+ signaling might affect energy production, ΔΨm was examined during Ca2+ oscillations in smooth muscle cells.
Chalmers, S., McCarron, J.G.
openaire   +4 more sources

A549 in-silico 1.0: A first computational model to simulate cell cycle dependent ion current modulation in the human lung adenocarcinoma.

open access: yesPLoS Computational Biology, 2021
Lung cancer is still a leading cause of death worldwide. In recent years, knowledge has been obtained of the mechanisms modulating ion channel kinetics and thus of cell bioelectric properties, which is promising for oncological biomarkers and targets ...
Sonja Langthaler   +8 more
doaj   +1 more source

The pros and cons of degeneracy

open access: yeseLife, 2014
Drugs could treat neuropathic pain more effectively if they simultaneously targeted two or more types of ion channel.
Jean-Marc Goaillard, Martial A Dufour
doaj   +1 more source

Criticality and degeneracy in injury-induced changes in primary afferent excitability and the implications for neuropathic pain

open access: yeseLife, 2014
Neuropathic pain remains notoriously difficult to treat despite numerous drug targets. Here, we offer a novel explanation for this intractability.
Stéphanie Ratté   +3 more
doaj   +1 more source

The relationship between respiration-related membrane potential slow oscillations and discharge patterns in mitral/tufted cells: what are the rules? [PDF]

open access: yesPLoS ONE, 2012
A slow respiration-related rhythm strongly shapes the activity of the olfactory bulb. This rhythm appears as a slow oscillation that is detectable in the membrane potential, the respiration-related spike discharge of the mitral/tufted cells and the ...
Virginie Briffaud   +4 more
doaj   +1 more source

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