Results 1 to 10 of about 121 (70)

Variable mechanisms of action of lithium during generating of membrane potential oscilations across the excitable membrane of the Nitela cell [PDF]

Zbornik Matice Srpske za Prirodne Nauke, 2012
This study presents results on variable mechanisms of lithium transport processes during generating of membrane potential oscillations across the very excitable membrane of the Nittela cell.
Radenović Čedomir N., Beljanski Miloš V., Maksimov Georgij V., Stanisavljev Dragomir R.   +3 more
doaj   +1 more source

Sodium-mediated plateau potentials in an identified decisional neuron contribute to feeding-related motor pattern genesis in Aplysia

Frontiers in Neural Circuits, 2023
Motivated behaviors such as feeding depend on the functional properties of decision neurons to provide the flexibility required for behavioral adaptation.
Alexis Bédécarrats, John Simmers, Romuald Nargeot   +2 more
doaj   +1 more source

Neuronal oscillations enhance stimulus discrimination by ensuring action potential precision.

PLoS Biology, 2006
Although oscillations in membrane potential are a prominent feature of sensory, motor, and cognitive function, their precise role in signal processing remains elusive.
Andreas T Schaefer, Kamilla Angelo, Hartwig Spors, Troy W Margrie   +3 more
doaj   +1 more source

A549 in-silico 1.0: A first computational model to simulate cell cycle dependent ion current modulation in the human lung adenocarcinoma.

PLoS Computational Biology, 2021
Lung cancer is still a leading cause of death worldwide. In recent years, knowledge has been obtained of the mechanisms modulating ion channel kinetics and thus of cell bioelectric properties, which is promising for oncological biomarkers and targets ...
Sonja Langthaler, Theresa Rienmüller, Susanne Scheruebel, Brigitte Pelzmann, Niroj Shrestha, Klaus Zorn-Pauly, Wolfgang Schreibmayer, Andrew Koff, Christian Baumgartner   +8 more
doaj   +1 more source

The pros and cons of degeneracy

eLife, 2014
Drugs could treat neuropathic pain more effectively if they simultaneously targeted two or more types of ion channel.
Jean-Marc Goaillard, Martial A Dufour
doaj   +1 more source

Criticality and degeneracy in injury-induced changes in primary afferent excitability and the implications for neuropathic pain

eLife, 2014
Neuropathic pain remains notoriously difficult to treat despite numerous drug targets. Here, we offer a novel explanation for this intractability.
Stéphanie Ratté, Yi Zhu, Kwan Yeop Lee, Steven A Prescott   +3 more
doaj   +1 more source

The relationship between respiration-related membrane potential slow oscillations and discharge patterns in mitral/tufted cells: what are the rules? [PDF]

PLoS ONE, 2012
A slow respiration-related rhythm strongly shapes the activity of the olfactory bulb. This rhythm appears as a slow oscillation that is detectable in the membrane potential, the respiration-related spike discharge of the mitral/tufted cells and the ...
Virginie Briffaud, Nicolas Fourcaud-Trocmé, Belkacem Messaoudi, Nathalie Buonviso, Corine Amat   +4 more
doaj   +1 more source

Regulation of [Ca2+]i oscillations and mitochondrial activity by various calcium transporters in mouse oocytes

Reproductive Biology and Endocrinology, 2020
Oocyte activation inefficiency is one of the reasons for female infertility and Ca2+ functions play a critical role in the regulation of oocyte activation.
Feng Wang, Ang Li, Tie-Gang Meng, Le-Yun Wang, Li-Juan Wang, Yi Hou, Heide Schatten, Qing-Yuan Sun, Xiang-Hong Ou   +8 more
doaj   +1 more source

Theoretical foundations of the sound analogue membrane potential that underlies coincidence detection in the barn owl

Frontiers in Computational Neuroscience, 2013
A wide variety of neurons encode temporal information via phase-locked spikes. In the avian auditory brainstem, neurons in the cochlear nucleus magnocellularis (NM) send phase-locked synaptic inputs to coincidence detector neurons in the nucleus ...
Go eAshida, Kazuo eFunabiki, Kazuo eFunabiki, Catherine E. Carr   +3 more
doaj   +1 more source

Dynamic response of model lipid membranes to ultrasonic radiation force. [PDF]

PLoS ONE, 2013
Low-intensity ultrasound can modulate action potential firing in neurons in vitro and in vivo. It has been suggested that this effect is mediated by mechanical interactions of ultrasound with neural cell membranes.
Martin Loynaz Prieto, Omer Ömer, Butrus T Khuri-Yakub, Merritt C Maduke   +3 more
doaj   +1 more source