Results 131 to 140 of about 57,363 (292)
Compensation of hyperexcitability with simulation-based inference
eLifeThe activity of healthy neuronal networks is tightly regulated, and a shift toward hyperexcitability can cause various problems, such as epilepsies, memory deficits, and motor disorders.
Daniel Müller-Komorowska, Tomoki Fukai
doaj +1 more source
Stage‐Specific Patterns of Imaging and Non‐Motor Biomarkers in Spinocerebellar Ataxia Type 3
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Advancements in disease‐modifying therapies for spinocerebellar ataxia Type 3 (SCA3) underscore the need for robust biomarkers to monitor disease progression and evaluate treatment efficacy. Although motor phenotypes have been well characterized, less is known about non‐motor and imaging‐based features across different disease stages.
Chun Li +17 more
wiley +1 more source
Heritability of Types of Pregeometry with Respect to Compositions of Structures
Известия Иркутского государственного университета: Серия "Математика"In this paper, we investigate how the pregeometry arising from the composition of two predicate signature structures inherits the types of pregeometries of the original stuctures.
S. B. Malyshev
doaj +1 more source
On “Relativistic Degeneracy.” [PDF]
Monthly Notices of the Royal Astronomical Society, 1935 openaire +2 more sources
The Association of Amyloid‐β and Tau With Synaptic Dysfunction in Alzheimer's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To clarify the relative contributions of amyloid and tau to synaptic dysfunction in Alzheimer's disease (AD). Methods We included 109 cognitively unimpaired and impaired individuals from the Geneva Memory Center with available CSF synaptic biomarkers (neurogranin, SNAP‐25, GAP‐43). Participants were stratified according to amyloid (A)
Fausto Roveta +11 more
wiley +1 more source
Degeneracy and long-range correlations [PDF]
, 2013 Degeneracy is a ubiquitous property of complex adaptive systems, which refers to the ability of structurally different components to perform the same function in some conditions and different functions in other conditions.
Delignières, D., Marmelat, Vivien
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A dual method for polar cuts in disjoint bilinear programming
Croatian Operational Research ReviewAs one branch of deterministic approaches to disjoint bilinear programming, cutting plane methods are renowned for its ability to systematically reduce the search space by adding cutting planes that are able to cut off regions deemed infeasible or ...
Xiaosong Ding, Jun Ma, Xi Chen, Chao Liu
doaj +1 more source
Myostatin/Smad3 in Spinal Muscular Atrophy: Biomarkers of Disease Severity and Treatment Response
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Given the role of Myostatin (MSTN) in muscle homeostasis and its modulation by current spinal muscular atrophy (SMA) therapies, we investigated serum MSTN and, for the first time, its downstream effector Smad3 as candidate non‐invasive biomarkers in SMA patients undergoing disease‐modifying therapies (DMTs).
Giorgia Riolo +11 more
wiley +1 more source
Four‐Year Cognitive Outcomes in Multiple Sclerosis: Associations With Lesion Myelin Integrity
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives Cognitive impairment is prevalent in patients with multiple sclerosis (MS) but whether lesion myelin integrity influences future cognitive outcomes remains unclear. We investigated the relationship between baseline lesion myelin water fraction (MWF) and cognitive performance 4 years later.
Iliana Pliska‐Bloch +9 more
wiley +1 more source
A computational model of view degeneracy
, 1999 ÐWe quantify the observation by Kender and Freudenstein [24] that degenerate views occupy a significant fraction of the viewing sphere surrounding an object.
John K. Tsotsos +2 more
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