Results 241 to 250 of about 45,478 (297)

GATA4‐Driven Transcription of HtrA1 Promotes Cellular Senescence in Ménière's Disease and Age‐Related Audio‐Vestibular Dysfunction

Advanced Science, EarlyView.
This study identifies the HDAC6/GATA4/HtrA1 axis as a critical driver of cellular senescence in the inner ear. GATA4 nuclear translocation, facilitated by HDAC6 downregulation, transcriptionally activates HtrA1, promoting hair cell senescence, SASP, and audio‐vestibular dysfunction in models of Ménière's disease and age‐related audio‐vestibular ...
Na Zhang, Na Li, Yan Wang, Jing Zhang, Jiahui Liu, Lei Chen, Yongdong Song, Yurong Mu, Yuechen Han, Yafeng Lyu, Xiaofei Li, Hanyue Wang, Jing Wang, Yao Lu, Zhaomin Fan, Daogong Zhang, Haibo Wang   +16 more
wiley   +1 more source

Electroacupuncture Improves the Learning and Memory by Modulating Hippocampal Glucose Metabolism through IGF1/IGF1R Signaling in Alzheimer's Disease

Advanced Science, EarlyView.
Electroacupuncture (EA) ameliorates learning and memory function in 5×FAD mice by regulating the brain glucose metabolic network. This neuroprotective effect is closely related to enhancing neuronal energy utilization via the IGF1/IGF1R signaling pathway.
Shengxiang Liang, Qingqing Zhang, Xiuxiu Wang, Lixin Peng, Xinru Ji, Jiawei Wang, Yusi Zhang, Jiayang Huang, Junchao Yang, Shiqi Zhan, Yiping Xiao, Weilin Liu, Lidian Chen   +12 more
wiley   +1 more source

Consilience in Causation: Causal Emergence Is Found Across Measures of Causation. [PDF]

Entropy (Basel)
Comolatti R, Hoel E.
europepmc   +1 more source

TRACER: a reliability-first GemNet baseline for trustworthy computational materials discovery. [PDF]

Sci Rep
Datta G, Sharif S, Banad Y.
europepmc   +1 more source

d-Wave Fermi Surface Instability in the Nematic Phase of Two Monolayer FeSe/SrTiO₃. [PDF]

Adv Sci (Weinh)
Tang CY, Peng XL, Yuan YH, Zhang P, Phan GN, Gao SY, Huang YB, Kong LY, Qian T, Li W, Xue QK, Wang ZQ, Jiang K, Sun YJ, Ding H.   +14 more
europepmc   +1 more source

Handed Magnon Propagation in Easy-Axis Antiferromagnetic α-Fe₂O₃. [PDF]

Adv Mater
Xu C, Park H, Zhang C, Yang H.
europepmc   +1 more source

Broadband Dielectric Response of Group-II Metal Oxide Monolayers: From Ionic to Electronic Polarization. [PDF]

Micromachines (Basel)
Yin P, Jia D, Tan D, Yang R.
europepmc   +1 more source

Degeneracy and Redundancy in Active Inference [PDF]

Cerebral Cortex, 2020
The notions of degeneracy and redundancy are important constructs in many areas, ranging from genomics through to network science. Degeneracy finds a powerful role in neuroscience, explaining key aspects of distributed processing and structure-function ...
Noor Sajid, Thomas Parr, Cathy J Price
exaly   +1 more source