An injectable, self‐healing COPRP hydrogel integrates structurally defined oxidized Polygonati rhizoma polysaccharide with carboxymethyl chitosan through dynamic Schiff‐base crosslinking. The bioactive matrix scavenges reactive oxygen species, suppresses neuroinflammation, protects dopaminergic neurons, and supports sustained levodopa release.
Peng Dai +10 more
wiley +1 more source
Patterns of degenerative change in the glenohumeral joint
Examination was made of 486 skeletons of subjects over the age of 60 years to study patterns of degenerative change in the glenohumeral joint. Three distinct types were found. Useful clinical implications are drawn from these distinctions.
JG Edelson
core +1 more source
Zinc transporter SLC39A14 sustains intracellular Zn2+ levels to activate SIRT3‑dependent ANXA2 deacetylation at K302. This modification weakens ANXA2‑mTOR binding and releases autophagic‑flux suppression in nucleus pulposus cells. Dysregulated Zn2+ homeostasis disrupts this axis to drive intervertebral disc degeneration.
Yuxin Jin +23 more
wiley +1 more source
Kvaliteta života osoba oboljelih od psorijatičnoga artritisa u usporedbi s reumatoidnim artritisom i degenerativnom bolešću zglobova [Quality of life in patients with psoriatic arthritis in comparison to rheumathoid arthritis and degenerative joint disease] [PDF]
Objectives. The main objective of this research is to compare quality of life in patients with PsA with the quality of life with patients suffering from RA and patients suffering from degenerative joint disease and to determine predictors of both ...
Grubišić, Frane
core +1 more source
Temporomandibular Joints (TMJ) is a bilateral fibrocartilage joint. This joint is unique in that it is a bilateral joint that functions as one unit. As with the other joints, many conditions affect TMJ causing It not to do its tasks.
Masoud Fallahi Motlagh +3 more
doaj +1 more source
Characterisation of the correlation between standing lordosis and degenerative joint disease in the lower lumbar spine in women and men: A radiographic ...
KJ Murray (14869126) +3 more
core
Retrospective Grid Cells in the Medial Entorhinal Cortex Encode Past Paths During Spatial Navigation
Retrospective grid cells are identified in the medial entorhinal cortex, with spatial firing patterns that become most grid‐like when activity is projected onto recently traversed locations. Their coding loses spatial precision in darkness and is disrupted during assisted movement, indicating that entorhinal representations incorporate recent path ...
Ruojin Liu +10 more
wiley +1 more source
The effect of anti-nerve growth factor monoclonal antibodies on the clinical signs of degenerative joint disease in cats. [PDF]
Seeley L.
europepmc +1 more source
Bioenergetic Materials for Tissue Regeneration: Modulating Metabolism to Promote Cellular Anabolism
Bioenergetic materials (BEMs) modulate cellular metabolism to promote tissue regeneration. Their principal mechanisms of action include metabolic substrate supplementation, metabolic enzyme modulation, organelle transfer, electrical current regulation, redox homeostasis modulation, and oxygen tension modulation.
Yuchen He +7 more
wiley +1 more source
Do owner-reported changes in mobility reflect measures of activity, pain and degenerative joint disease in cats? [PDF]
Maniaki E +3 more
europepmc +1 more source

