Results 11 to 20 of about 4,421 (195)

Insulin degludec

open access: yesJournal of Mahatma Gandhi Institute of Medical Sciences, 2013
Insulin analogues have revolutionized the treatment of diabetes mellitus, and the advent of newer insulin analogues have provided better glycemic control with lesser incidence of hypoglycemia.
Vishakha V Jain, Omprakash Gupta
doaj   +3 more sources

Insulin degludec and insulin degludec/insulin aspart in Ramadan: A single center experience

open access: yesIndian Journal of Endocrinology and Metabolism, 2016
This study aimed to document the utility and safety of insulin degludec (IDeg) and insulin degludec aspart (IDegAsp) in persons with type 2 diabetes, observing the Ramadan fast.
Sanjay Kalra
doaj   +4 more sources

Efficacy and safety of ultra-long-acting insulin degludec

open access: yesTherapeutic Advances in Endocrinology and Metabolism, 2012
All patients with type 1 diabetes and significant numbers of those with type 2 diabetes are treated with insulin. Nonadherence to insulin regimen can impact glycaemic control.
Ammar Wakil, Stephen L. Atkin
doaj   +2 more sources

Glargine and degludec: Solution behaviour of higher dose synthetic insulins [PDF]

open access: yesScientific Reports, 2017
Single, double and triple doses of the synthetic insulins glargine and degludec currently used in patient therapy are characterised using macromolecular hydrodynamic techniques (dynamic light scattering and analytical ultracentrifugation) in an attempt ...
Gary G. Adams   +10 more
doaj   +4 more sources

Insulin degludec is a new ultra-long-acting insulin analogue [PDF]

open access: yesСахарный диабет, 2014
Achieving optimal glycemic control is an important aspect of preventing and slowing the progression of diabetes-associated complications, and reducing the cost of their treatment.
Ivan Ivanovich Dedov   +1 more
doaj   +2 more sources

United States experience of insulin Degludec alone or in combination for type 1 and type 2 diabetes

open access: yesDrug Design, Development and Therapy, 2017
Marc Rendell1,2 1The Rose Salter Medical Research Foundation, 2The Association of Diabetes Investigators, Newport Coast, CA, USA Abstract: Insulin degludec has been the product of a sophisticated and systematic biochemical engineering program which ...
Rendell M
doaj   +1 more source

Switching from Insulin Degludec plus Dipeptidyl Peptidase-4 Inhibitor to Insulin Degludec/Liraglutide Improves Glycemic Variability in Patients with Type 2 Diabetes: A Preliminary Prospective Observation Study

open access: yesJournal of Diabetes Research, 2022
Incretins reduce glycemic variability (GV) in patients with type 2 diabetes, but it is unknown whether switching from a combination of basal insulin and a DPP-4 inhibitor to insulin degludec/liraglutide (IDegLira) improves GV. We performed an exploratory
Yuki Oe   +11 more
doaj   +2 more sources

Conversion from insulin glargine U-100 to insulin glargine U-300 or insulin degludec and the impact on dosage requirements

open access: yesTherapeutic Advances in Endocrinology and Metabolism, 2018
Background: We wanted to determine whether basal insulin requirements change when patients transition from insulin glargine U-100 (Gla-100) to insulin glargine U-300 (Gla-300) or insulin degludec.
Scott M. Pearson, Jennifer M. Trujillo
doaj   +2 more sources

Preserved pharmacokinetics and pharmacodynamics of insulin degludec and liraglutide when administered as insulin degludec/liraglutide in a Chinese population [PDF]

open access: yesJournal of Diabetes Investigation, 2022
We report the findings of a single‐dose, randomized, three‐period cross‐over, clinical trial in healthy Chinese individuals (n = 24) comparing the pharmacokinetics of insulin degludec/liraglutide (IDegLira) with its individual components. Furthermore, we
Hongzhong Liu   +6 more
doaj   +3 more sources

IDeglira vs insulin degludec for type 2 diabetes: a systematic review and meta-analysis [PDF]

open access: yesFrontiers in Endocrinology
ObjectivesThis systematic review and meta-analysis was to evaluate and compare the efficacy and safety profiles of IDegLira versus insulin degludec in the management of type 2 diabetes (T2D).MethodsA comprehensive search was systematically conducted ...
Yang Liu   +6 more
doaj   +2 more sources

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