Results 81 to 90 of about 23,224 (220)

Alterations in antigenic structure of gonadotropins following deglycosylation

open access: yesBioscience Reports, 1988
Radioimmunological techniques were utilized to probe possible changes in conformation of gonadotropins (human chorionic gonadotropin-hCG; and ovine luteinizing hormone—oLH) following chemical deglycosylation (DG-hCG and DG-LH). All antisera produced in rabbits, rats or mice contained antibodies that were specific to the deglycosylated hormones with the
M R, Sairam, J, Linggen, G N, Bhargavi
openaire   +2 more sources

The Arabidopsis NPF7.2 mediates coumarin uptake for root iron acquisition

open access: yesNew Phytologist, Volume 250, Issue 3, Page 1619-1633, May 2026.
Summary Iron (Fe) is a transition metal necessary for achieving essential physiological processes throughout the plant lifecycle. In Arabidopsis thaliana, secreting Fe‐mobilizing coumarins (FMC) is a key mechanism enabling roots to acquire nonbioavailable Fe present in soils.
Shunsuke Watanabe   +7 more
wiley   +1 more source

Real-Time Analysis on Drug-Antibody Ratio of Antibody-Drug Conjugates for Synthesis, Process Optimization, and Quality Control

open access: yesScientific Reports, 2017
Drug-antibody ratio (DAR) of antibody-drug conjugates (ADCs) is important for their therapeutic efficacy and pharmacokinetics, therefore control on DAR in synthesis process is a key for ADC quality control.
Yubo Tang   +6 more
doaj   +1 more source

The Impact of Steroidal Glycoalkaloids on the Physiology of Phytophthora infestans, the Causative Agent of Potato Late Blight

open access: yesMolecular Plant-Microbe Interactions, 2017
Steroidal glycoalkaloids (SGAs) are plant secondary metabolites known to be toxic to animals and humans and that have putative roles in defense against pests.
Paul Dahlin   +4 more
doaj   +1 more source

Engineering a highly active thermophilic β-glucosidase to enhance its pH stability and saccharification performance [PDF]

open access: yes, 2016
BACKGROUND: β-Glucosidase is an important member of the biomass-degrading enzyme system, and plays vital roles in enzymatic saccharification for biofuels production.
Bin Yao   +7 more
core   +1 more source

Partial deglycosylation of blood-group-specific glycoproteins [PDF]

open access: yesBiochemical Journal, 1980
The time course for the partial deglycosylation of blood-group-specific glycoproteins from human ovarian-cyst fluids with 0.25 M-H2SO4/acetic acid and 6 M-HCl in methanol was studied. Either reagent readily removed about 80% of the carbohydrate from the glycoproteins to leave non-diffusible glycopeptides that contain N-acetylgalactosamine as the ...
openaire   +2 more sources

One‐Step and Universal Strategy for the Synthesis of Hypermodified Uracil Phosphoramidites acp3U and cmnm5U

open access: yesChemistry – A European Journal, Volume 32, Issue 16, 25 April 2026.
One‐step, highly efficient, and scalable synthesis of acp3U phosphoramidite is described, as well as a new alternative synthesis of cmnm5U phosphoramidite from a highly versatile intermediate. Latter could be scaled‐up, split, and aliquots turned simultaneously into cmnm5U, nm5U, and mnm5U.
Ewa Mejdr   +3 more
wiley   +1 more source

PNGase Sensitivity Assay to Study the Folding Status of Proteins

open access: yesBio-Protocol, 2016
This protocol aims to evaluate folding status of proteins, utilizing peptide:N-glycanase (PNGase) sensitivity. In the cytosol, PNGase works as a deglycosylation-enzyme.
Satoshi Ninagawa, Kazutoshi Mori
doaj   +1 more source

The Nicastrin ectodomain adopts a highly thermostable structure [PDF]

open access: yes, 2011
Nicastrin is a type I transmembrane glycoprotein, which is part of the high molecular weight gamma-secretase complex. gamma-Secretase is one of the key players associated with the generation of Alzheimer's disease pathology, since it liberates the ...
Beyer, Klaus   +6 more
core   +2 more sources

Bacteria and Fungi Synergistically Reprogram Flavonoid Metabolites in the Pericarp of Citrus Reticulata 'Chachi' During Storage

open access: yesAdvanced Science, Volume 13, Issue 22, 17 April 2026.
The authors employed widely targeted metabolomics, microbial amplicon sequencing, and fermentation assays to investigate the microbiome 's influence on PCRC 's (pericarp of Citrus reticulata ' Chachi ') flavonoid profile over 0–19 years of storage. Based on the correlation analysis, solid‐state and liquid‐state fermentation, and catalytic activity ...
Jianmu Su   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy