Results 91 to 100 of about 17,182 (211)
Deglycosylation systematically improves N-glycoprotein identification in liquid chromatography-tandem mass spectrometry proteomics for analysis of cell wall stress responses in Saccharomyces cerevisiae lacking Alg3p [PDF]
, 2013 Post-translational modification of proteins with glycosylation is of key importance in many biological systems in eukaryotes, influencing fundamental biological processes and regulating protein function. Changes in glycosylation are therefore of interest
Bailey, Ulla-Maja, Schulz, Benjamin L.
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The role of epithelial cell adhesion molecule N-glycosylation on apoptosis in breast cancer cells
Tumor Biology, 2017 Glycosylation of cell surface proteins plays an important role in the regulation of apoptosis. It has been demonstrated that knockdown of epithelial cell adhesion molecule promoted apoptosis, inhibited cell proliferation, and caused cell-cycle arrest. In
Dandan Zhang +6 more
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Journal of Pharmacological Sciences, 2004 Orally ingested ginsenoside passes through the stomach and small intestine without decomposition by either gastric juice or liver enzymes into the large intestine, where ginsenoside is deglycosylated by colonic bacteria followed by transit to the ...
Hideo Hasegawa
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, 2022 Aim: The 20(S)-ginsenoside Rh2 (Rh2) is being developed as a new antitumor drug. However, to date, little is known about the kinetics of its deglycosylation metabolite (protopanoxadiol) (PPD) following Rh2 administration.
Yang Sai (2125750) +14 more
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Haematologica, 2012 Background Storing platelets for transfusion at room temperature increases the risk of microbial infection and decreases platelet functionality, leading to out-date discard rates of up to 20%.
Eelo Gitz +6 more
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, 1989 In order to investigate the lectin-binding properties of the photoreceptor cGMP-gated channel, solubilized and purified channel protein was incubated with immobilized lectins followed by reconstitution of unbound proteins.
Wohlfahrt, P., Cook, N., Müller, H.
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Deglycosylation of wogonoside enhances its anticancer potential
Journal of Cancer Research and Therapeutics, 2018 Scutellaria baicalensis is commonly used in Asia as an herbal medicine to treat a variety of ailments, including cancer. Wogonoside, one major constituent of S. baicalensis, can be primarily converted to wogonin through deglycosylation via enteric microbiome metabolism.The antiproliferative effects of the glycoside (wogonoside) and its deglycosylated ...
Chong-Zhi, Wang +5 more
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Molecules, 2016 A method using liquid chromatography-electrospray ionization ion trap mass spectrometry was established for the identification of metabolites in feces, urine and bile in rats after oral administration of 3′,4′-dimethoxy flavonol-3-β-d-glucopyranoside ...
Yuan Zhu +6 more
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Introducing deglycosylation in targeted biomarker analysis using fetuin as a model protein
, 2008 It is believed that protein analysis by LC-MS will be an important diagnostic tool for different kind of diseases in the future. Proteins can not always be directly analyzed by LC-MS, several sample preparation steps can be necessary.
Nikolaisen, Mats
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, 2022 Aim: The 20(S)-ginsenoside Rh2 (Rh2) is being developed as a new antitumor drug. However, to date, little is known about the kinetics of its deglycosylation metabolite (protopanoxadiol) (PPD) following Rh2 administration.
Yang Sai (2125750) +14 more
core +1 more source