Results 1 to 10 of about 4,101,114 (282)

CdS/Bi12O17Cl2 Heterostructure Promotes Visible-Light-Driven Photocatalytic CH4 Generation and Phenol Conversion

open access: yesInternational Journal of Photoenergy, 2022
We report a heterojunction photocatalyst by coupling CdS with Bi12O17Cl2 via a facile thermal annealing process. Such heterostructure can promote the charge separation between CdS and Bi12O17Cl2, thereby leading to a considerable improvement on the ...
Dandan Hu   +10 more
doaj   +1 more source

The oasis regional small and medium lake water transparency monitoring research and impact factor analysis based on field data combined with high resolution GF-1 satellite data

open access: yesJournal of Freshwater Ecology, 2021
Water transparency is an important parameter to characterize water quality of rivers, lakes and wetlands. We measured the water quality data such as water transparency and the water spectral data of Shahu Lake. GF-1 image data were preprocessed to assure
Zhenghu Ma   +6 more
doaj   +1 more source

Targeted degradation of ⍺-synuclein aggregates in Parkinson’s disease using the AUTOTAC technology

open access: yesMolecular Neurodegeneration, 2023
Background There are currently no disease-modifying therapeutics for Parkinson’s disease (PD). Although extensive efforts were undertaken to develop therapeutic approaches to delay the symptoms of PD, untreated α-synuclein (α-syn) aggregates cause ...
Jihoon Lee   +14 more
doaj   +1 more source

Ion Channels and Pumps in Autophagy: A Reciprocal Relationship

open access: yesCells, 2021
Autophagy, the process of cellular self-degradation, is intrinsically tied to the degradative function of the lysosome. Several diseases have been linked to lysosomal degradative defects, including rare lysosomal storage disorders and neurodegenerative ...
Hussein Abuammar   +6 more
doaj   +1 more source

Structure-based design of a phosphotyrosine-masked covalent ligand targeting the E3 ligase SOCS2

open access: yesNature Communications, 2023
The Src homology 2 (SH2) domain recognizes phosphotyrosine (pY) post translational modifications in partner proteins to trigger downstream signaling. Drug discovery efforts targeting the SH2 domains have long been stymied by the poor drug-like properties
Sarath Ramachandran   +10 more
doaj   +1 more source

Integration of ARTP Mutation and Adaptive Laboratory Evolution to Reveal 1,4-Butanediol Degradation in Pseudomonas putida KT2440

open access: yesMicrobiology Spectrum, 2023
Biotransformation of plastics or their depolymerization monomers as raw materials would offer a better end-of-life solutions to the plastic waste dilemma. 1,4-butanediol (BDO) is one of the major depolymerization monomers of many plastics polymers.
Xiujuan Qian   +6 more
doaj   +1 more source

Identification and expression analysis of UV-B photoreceptor UVR8 genes in Apocynum venetum and A. cannabinum

open access: yesGuangxi Zhiwu, 2023
In the processes of plants response to UV-B, the UV-B photoreceptor UVR8 (UV Resistance Locus 8) plays an important role in the regulation of photomorphogenesis, growth and metabolism of plants.
Jinfeng CHE   +7 more
doaj   +1 more source

MYC Degradation [PDF]

open access: yesCold Spring Harbor Perspectives in Medicine, 2014
The MYC oncoprotein is an essential transcription factor that regulates the expression of many genes involved in cell growth, proliferation, and metabolic pathways. Thus, it is important to keep MYC activity in check in normal cells in order to avoid unwanted oncogenic changes.
Amy S, Farrell, Rosalie C, Sears
openaire   +2 more sources

The Thermal degradation of Bisphenol A Polycarbonate in Air [PDF]

open access: yes, 2005
The thermal degradation of polycarbonate in air was studied as a function of mass loss using TGA/FTIR, GC/MS and LC/MS. In the main degradation region, 480–560 °C, the assigned structures of smaller molecules and linear molecules that evolved in air were
Jang, Bok Nam, Wilkie, Charles A.
core   +2 more sources

Gambogic Acid Is a Tissue-Specific Proteasome Inhibitor In Vitro and In Vivo

open access: yesCell Reports, 2013
Gambogic acid (GA) is a natural compound derived from Chinese herbs that has been approved by the Chinese Food and Drug Administration for clinical trials in cancer patients; however, its molecular targets have not been thoroughly studied.
Xiaofen Li   +28 more
doaj   +1 more source

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