Results 31 to 40 of about 2,986,953 (305)

"TO THE DEGRADATION OF THE SPECTATOR." [PDF]

The Lancet, 1896
n ...
openaire   +2 more sources

Design of a Cereblon construct for crystallographic and biophysical studies of protein degraders

Nature Communications
The ubiquitin E3 ligase cereblon (CRBN) is the target of therapeutic drugs thalidomide and lenalidomide and is recruited by most targeted protein degraders (PROTACs and molecular glues) in clinical development. Biophysical and structural investigation of
Alena Kroupova, Valentina A. Spiteri, Zoe J. Rutter, Hirotake Furihata, Darren Darren, Sarath Ramachandran, Sohini Chakraborti, Kevin Haubrich, Julie Pethe, Denzel Gonzales, Andre J. Wijaya, Maria Rodriguez-Rios, Manon Sturbaut, Dylan M. Lynch, William Farnaby, Mark A. Nakasone, David Zollman, Alessio Ciulli   +17 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Method for quantification of microplastic release from plastic-based materials during weathering

Microplastics and Nanoplastics
Most microplastics (MPs) are generated as a result of photodegradation during the life of plastic products and after the end-of-life as mismanaged waste.
Edgars Kuka, Ingeborga Andersone, Dace Cirule, Lotars Olivers Vasiljevs, Anrijs Verovkins, Errj Sansonetti, Galina Dobele, Bruno Andersons   +7 more
doaj   +1 more source

Andi1974/Forest-degradation-monitoring: DeltaNBR

, 2017
Repository for technical data dealing with (semi)-evergreen forest degradation ...
Andreas Langner, Andreas Langner (368758)   +1 more
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Development of an oncogenic dedifferentiation SOX signature with prognostic significance in hepatocellular carcinoma

BMC Cancer, 2019
Background Gradual loss of terminal differentiation markers and gain of stem cell-like properties is a major hall mark of cancer malignant progression.
Mei-Mei Li, Yun-Qiang Tang, Yuan-Feng Gong, Wei Cheng, Hao-Long Li, Fan-En Kong, Wen-Jie Zhu, Shan-Shan Liu, Li Huang, Xin-Yuan Guan, Ning-Fang Ma, Ming Liu   +11 more
doaj   +1 more source

New organic matter degradation proxies: Valid in lake systems? [PDF]

, 2004
We determined concentrations and diagenetic state of organic matter in two cores from Lake Zug, Switzerland. To obtain a general picture of organic matter decay in the lake, we measured bulk parameters such as total organic carbon, total nitrogen, and ...
C. J. Schubert, M. Dittrich, G. L. Cowie, S. Peiffer, Peiffer, S., A. N. Meckler, Schubert, C. J., Cowie, G. L., Dittrich, M., Meckler, A. N., Schubert, C.J. (author), Meckler, A.N. (author), Dittrich, M. (author), Peiffer, S. (author), Cowie, G.L. (author)   +14 more
core   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Structure Characterization and Electrical Properties of Sn0.9Ga0.1P2O7/KH2PO4/KPO3 Composite Electrolyte for Medium Temperature Fuel Cells

International Journal of Electrochemical Science, 2020
In this study, Sn0.9Ga0.1P2O7/KH2PO4/KPO3 was synthesized by solid-phase method. The sample was characterized by Raman spectrometer and X-ray diffractometer.
Yan Han, Zikun Rong, Tianhui Hu, Peng Sun, Lin Sun, Hui Miao   +5 more
doaj   +1 more source