Results 21 to 30 of about 4,509,963 (335)

Gambogic Acid Is a Tissue-Specific Proteasome Inhibitor In Vitro and In Vivo

Cell Reports, 2013
Gambogic acid (GA) is a natural compound derived from Chinese herbs that has been approved by the Chinese Food and Drug Administration for clinical trials in cancer patients; however, its molecular targets have not been thoroughly studied.
Xiaofen Li, Shouting Liu, Hongbiao Huang, Ningning Liu, Chong Zhao, Siyan Liao, Changshan Yang, Yurong Liu, Canguo Zhao, Shujue Li, Xiaoyu Lu, Chunjiao Liu, Lixia Guan, Kai Zhao, Xiaoqing Shi, Wenbin Song, Ping Zhou, Xiaoxian Dong, Haiping Guo, Guanmei Wen, Change Zhang, Lili Jiang, Ningfang Ma, Bing Li, Shunqing Wang, Huo Tan, Xuejun Wang, Q. Ping Dou, Jinbao Liu   +28 more
doaj   +1 more source

A Multi-Scenario Prediction and Spatiotemporal Analysis of the Land Use and Carbon Storage Response in Shaanxi

Remote Sensing, 2023
The role of carbon sequestration in terrestrial ecosystems is crucial for achieving carbon neutrality. This study primarily focuses on examining the carbon storage in Shaanxi Province under different land-use scenarios.
Xindong Wei, Shuyuan Zhang, Pingping Luo, Shuomeng Zhang, Huanyuan Wang, Dehao Kong, Yuanyuan Zhang, Yang Tang, Shuo Sun   +8 more
doaj   +1 more source

Methods to Detect AUTOphagy-Targeting Chimera (AUTOTAC)-mediated Targeted Protein Degradation in Tauopathies

Bio-Protocol, 2023
Targeted protein degradation (TPD) facilitates the selective elimination of unwanted and pathological cellular cargoes via the proteasome or the lysosome, ranging from proteins to organelles and pathogens, both within and outside the cell.
Min Lee, Su Kim, Hee Kim, Su Jin Lee, Ji Su Lee, Yong Tae Kwon, Chang Ji   +6 more
doaj   +1 more source

Nickel pyrithione induces apoptosis in chronic myeloid leukemia cells resistant to imatinib via both Bcr/Abl-dependent and Bcr/Abl-independent mechanisms

Journal of Hematology & Oncology, 2016
Background Acquired imatinib (IM) resistance is frequently characterized by Bcr-Abl mutations that affect IM binding and kinase inhibition in patients with chronic myelogenous leukemia (CML).
Xiaoying Lan, Chong Zhao, Xin Chen, Peiquan Zhang, Dan Zang, Jinjie Wu, Jinghong Chen, Huidan Long, Li Yang, Hongbiao Huang, Bing Z. Carter, Xuejun Wang, Xianping Shi, Jinbao Liu   +13 more
doaj   +1 more source

A novel profluorescent dinitroxide for imaging polypropylene degradation [PDF]

, 2008
Free-radical processes underpin the thermo-oxidative degradation of polyolefins. Thus, to extend the lifetime of these polymers, stabilizers are generally added during processing to scavenge the free radicals formed as the polymer degrades.
Fairfull-Smith, Kathryn E., Blinco, James P., Keddie, Daniel J., George, Graeme A., Bottle, Steven E.   +4 more
core   +2 more sources

Downregulation of Linc00173 increases BCL2 mRNA stability via the miR-1275/PROCA1/ZFP36L2 axis and induces acquired cisplatin resistance of lung adenocarcinoma

Journal of Experimental & Clinical Cancer Research, 2023
Background LINC00173 had been reported as a cisplatin (cis-diamminedichloroplatinum, DDP) chemotherapy-resistant inducer in small-cell lung cancer (SCLC) and lung squamous cell carcinoma (LUSC). This study aimed to display reverse data for LINC00173 as a
Xingyu Tao, Yang Li, Songqing Fan, Liyang Wu, Jianyang Xin, Yun Su, Xiaoyang Xian, Yingying Huang, Rongquan Huang, Weiyi Fang, Zhen Liu   +10 more
doaj   +1 more source

Design of portable 3-axis filament winding machine with inexpensive control system

Journal of Mechanical Engineering and Sciences, 2018
Filament winding technology is one of the fundamental fabrication methods invcomposite material fields, which has a high degree of automation. It is the process invwhich continuous strands or filament of fibres is wound on the mandrel, which is suitable
Ma Quanjin, M.R.M. Rejab, I.M. Sahat, M. Amiruddin, D. Bachtiar, J.P. Siregar, M.I. Ibrahim   +6 more
doaj   +1 more source

Correction: TRPC6-dependent Ca2+ signaling mediates airway inflammation in response to oxidative stress via ERK pathway

Cell Death and Disease, 2020
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Qingzi Chen, Yubo Zhou, Lifen Zhou, Zhaodi Fu, Chuntao Yang, Lei Zhao, Shuni Li, Yan Chen, Yousen Wu, Zhenwei Ling, Yufeng Wang, Jianrong Huang, Jianhua Li   +12 more
doaj   +1 more source

Analysis of Scarp Profiles: Evaluation of Errors in Morphologic Dating [PDF]

, 1993
Morphologic analysis of scarp degradation can be used quantitatively to determine relative ages of different scarps formed in cohesionless materials, under the same climatic conditions.
Avouac, Jean-Philippe
core   +1 more source

Crushing behaviour of composite square honeycomb structure: a finite element analysis

Journal of Mechanical Engineering and Sciences, 2017
This paper investigates the compression properties of square honeycomb core materials based on glass fibre reinforced plastic. The objective of this project is to determine the failure strength and energy absorption of the square honeycomb structure and
Z. Ansari, C.W. Tan, M.R.M. Rejab, D. Bachtiar, J. Siregar, M.Y.M. Zuhri, N.S.D.M. Marzuki   +6 more
doaj   +1 more source