Results 311 to 320 of about 116,525 (341)
Some of the next articles are maybe not open access.
Markers of Mast Cell Degranulation
Methods, 1997Mast cells are the primary effector cells of immediate hypersensitivity reactions in humans. Upon mast cell activation both preformed and newly synthesized mediators are secreted. Histamine can be measured by fluorometric assays, radioenzymatic assays, and immunoassays.
A D, Hogan, L B, Schwartz
openaire +2 more sources
Neutrophil degranulation: therapeutic targets in [NTP]O mediated neutrophil degranulation
Medical Hypotheses, 2004Extracellular nucleotide-induced stimulation and activation of peripheral blood neutrophil and subsequent degranulation plays a critical role in immediate type hypersensitivity reaction and other inflammatory diseases. The extracellular nucleotides stimulate a P2Y receptor(s) on human PMN with the pharmacological profile similar to that of the P2Y2 ...
openaire +2 more sources
Archives of Dermatology, 1965
A case report of coal tar hypersensitivity is presented. The clinical picture was one of psoriatic erythroderma. Confirmation of this hypersensitivity was demonstrated by observing morphologic changes in the circulating basophil following inhalation of crude coal tar vapor. Three control subjects showed no response to a similar challenge.
H M, PARNES, W B, SHELLEY
openaire +2 more sources
A case report of coal tar hypersensitivity is presented. The clinical picture was one of psoriatic erythroderma. Confirmation of this hypersensitivity was demonstrated by observing morphologic changes in the circulating basophil following inhalation of crude coal tar vapor. Three control subjects showed no response to a similar challenge.
H M, PARNES, W B, SHELLEY
openaire +2 more sources
Measuring Degranulation of Mast Cells
Current Protocols in Immunology, 1993AbstractThis unit describes methods for measuring exocytosis of preformed mediators from secretory granules as an indication of IgE receptor‐mediated activation of mast cells. The first basic protocol describes the measurement of biogenic amines (serotonin and histamine) secreted by activated rodent mast cells (for serotonin) or rodent and human mast ...
R J, Hohman, S C, Dreskin
openaire +2 more sources
Nephron, 2000
<i>Background/Aims: </i>Degranulation of polymorphonuclear leukocytes (PMN) during hemodialysis (HD) is usually assessed by measuring degranulation products. However, this process might also be estimated by the assessment of cell surface markers.
Grooteman, M P +6 more
openaire +3 more sources
<i>Background/Aims: </i>Degranulation of polymorphonuclear leukocytes (PMN) during hemodialysis (HD) is usually assessed by measuring degranulation products. However, this process might also be estimated by the assessment of cell surface markers.
Grooteman, M P +6 more
openaire +3 more sources
Cannabinoid induced degranulation of rabbit neutrophils
Biochemical and Biophysical Research Communications, 1982Abstract We have examined the effects of various cannabinoids on the degranulation of rabbit peritoneal neutrophils. Several cannabinoids were found to cause a dose-dependent and noncytotoxic release of lysosomal enzymes from the neutrophils. The degranulation induced by cannabidiol is rapid ( t 1 2 = 2.3 min ), and enhanced by ...
P H, Naccache +4 more
openaire +2 more sources
Granulation-Degranulation Processes
2020In this chapter, we discuss the concept of information granulation and degranulation as one of the fundamental computing paradigms of Granular Computing supporting interaction with real-world environment. In the setting of fuzzy sets, the wording fuzzification-defuzzification is commonly used.
openaire +1 more source
IgA-induced eosinophil degranulation.
The Journal of Immunology, 1989Abstract Eosinophils play an important role as effector cells in allergic, parasitic, and other conditions. The mechanism(s) by which eosinophils mediate their effector functions was studied by incubation of human normodense eosinophils with Sepharose beads coupled to various Ig isotypes as targets.
R I, Abu-Ghazaleh +4 more
openaire +2 more sources
Degranulation mechanisms in human leukemic basophils
Clinical Immunology and Immunopathology, 1976Abstract The peripheral blood basophils of a patient with chronic myelogenous leukemia, basophilic phase (up to 85% of circulating leukocytes were mature basophils), and substantially elevated levels of urine histamine were studied in the electron microscope in an attempt to relate morphologic changes to possible mechanisms of mediator secretion.
A M, Dvorak +4 more
openaire +2 more sources
Neutrophil Degranulation Induced by Haemophilus ducreyi
bchm, 2001Haemophilus ducreyi is the causative bacterium of genital ulcers, which are collectively known as chancroid. Little is known about the cytotoxicity of H. ducreyi. The virulent strains are relatively resistant to phagocytosis and apoptosis by neutrophils.
B, Odhav, A, Hoosen, W, Sturm
openaire +2 more sources