ABSTRACT Background Toll‐like receptors (TLRs) play a critical role in innate immunity by recognizing pathogen‐associated and damage‐associated molecular patterns. Genetic polymorphisms in TLR genes can modulate immune responses and have been implicated in the outcomes of allogeneic hematopoietic cell transplantation (HCT).
Takaaki Konuma +10 more
wiley +1 more source
Crosstalk Between Allergic Inflammation and Autophagy. [PDF]
Jeoung J, Kim W, Jeoung D.
europepmc +1 more source
Proteinases and proteinase inhibitors in ejaculates of men with adnex affections [PDF]
Brunner, H. +9 more
core
Cortisol has been linked to poor cancer prognosis but can also be released during exercise. This study shows that transient cortisol exposure, as seen with exercise, does not impair T cell effector functions. In contrast, chronic cortisol signalling suppresses T cell functionality and promotes cancer cell proliferation, highlighting the importance of ...
Thy Viet Luu +5 more
wiley +1 more source
Cashew nut oligopeptide inhibits mast cell degranulation by suppressing activation of the NF-Κb signalling pathway. [PDF]
Chen D, Zhou X, Zhang Y, Chen J.
europepmc +1 more source
Effect of depression and serotonin reuptake inhibitors antidepressant treatment during pregnancy on protein expression in the human placenta: A quantitative proteomics analysis. [PDF]
Ok L +10 more
europepmc +1 more source
Spatial Transcriptomic Assessments of Gene Expression Profiles in Human Peri‐Implant Lesions
ABSTRACT Aim To analyse gene expression profiles in human tissue samples obtained from dental implant sites with or without peri‐implantitis. Materials and Methods Soft‐tissue biopsy samples obtained from patients presenting with implants with severe peri‐implantitis and adjacent reference implants with no signs of peri‐implantitis were analysed by ...
C. Dionigi +4 more
wiley +1 more source
Dynamics of NK cell subsets following autologous hematopoietic stem cell transplantation in adult oncologic patients. [PDF]
Astarloa-Pando G +20 more
europepmc +1 more source
This study employed GeoMx digital spatial profiling of thrombi retrieved by mechanical thrombectomy from ischemic stroke patients. Spatial transcriptomic analysis revealed distinct immune signatures, suggesting subtype‐specific mechanisms of immunothrombosis. Neutrophil extracellular trap–related pathways were enriched in cardioembolic thrombi, whereas
Sugyeong Jo +8 more
wiley +1 more source
Pediatric Anaphylaxis in the Emergency Department: From Mechanisms to Personalized Care. [PDF]
Mansour GK, AlGoraini Y.
europepmc +1 more source

