Results 331 to 340 of about 137,298 (386)

Development of Granzyme A Turn‐ON Fluorescent Activity‐Based Probes

ChemBioChem, Volume 26, Issue 24, December 11, 2025.
A quenched activity‐based probe, featuring the Ile–Gly–Asn–Arg recognition sequence, a phenyl phosphinate ester warhead, and a near‐infrared sulfo‐Cy5/QSY21 fluorophore/quencher pair, generates a fluorescence signal only upon reaction with active granzyme A (GzmA). With its high reactivity, selectivity, and cell permeability, this turn‐ON probe enables
Sebastian M. Malespini, Muhammad Kazim, Euna Yoo   +2 more
wiley   +1 more source

Framework humanization enhances GM3(Neu5Gc)-targeting CAR-T cell function by reducing tonic signaling. [PDF]

Front Immunol
Tu J, Li X, Zhu Y, Li S, Zhang G, He Y, Zhang C, Lu Z.   +7 more
europepmc   +1 more source

Novel and unscrutinized immune entities of the zebrafish gut

FEBS Letters, Volume 599, Issue 23, Page 3444-3455, December 2025.
Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil, Marine Mantel, Julia Soh, Serge Mostowy, Sylvia Brugman, Gilles Claude Vanwalleghem   +5 more
wiley   +1 more source

The effect of COVID-19 and sex differences on natural killer cell cytotoxicity. [PDF]

Front Cell Infect Microbiol
Dagar A, Polyak MJ, Mok ACH, Feehan D, Potemkin M, Tremblay A, Mody CH.   +6 more
europepmc   +1 more source

Tackling Allergic Airway Inflammation with Organic Sheet‐Like Nanoplatforms by Targeted Elimination of Epithelial Small Extracellular Vesicles

Advanced Science, Volume 12, Issue 46, December 11, 2025.
In this work, “inorganic‐free” nanosheets, named PNSE are developed using template‐based synthesis technology. The functionalized organic nanosheets exhibit low cytotoxicity, mild protein adsorption, and potent binding efficacy to epithelial sEVs.
Zhaoxu Tu, Junyan Lin, Zhixin Li, Yuefei Zhu, Changyi Xu, Zihan Qiu, Qiumin Wang, Yang Ye, Yihui Wen, Jian Li, Kam W. Leong, Weiping Wen   +11 more
wiley   +1 more source

The role of mast cells in allergic rhinitis. [PDF]

PeerJ
Zhang J, Xie X, Ma R, Liu P.
europepmc   +1 more source

Global genome analysis identifies glycolipids and lipoteichoic acid alanylation as contributors to group B streptococcal diabetic wound infection. [PDF]

Cell Rep
Joyce LR, Akbari MS, Nguyen DT, Spencer BL, Rahkola J, McIver KS, Horswill AR, Doran KS, Keogh RA.   +8 more
europepmc   +1 more source

Glutaminase activity maintains NK cell cytotoxicity through metabolic regulation of effector function. [PDF]

J Inflamm (Lond)
Jedlička M, Feglarová T, Švubová V, Mašínová E, Graman V, Kuglerová K, Szabová J, Jahan F, Korhonen M, Kuželová K, Hortová-Kohoutková M, Frič J.   +11 more
europepmc   +1 more source

The Dual Role of Nitric Oxide in Allergic Rhinitis: From the NO/cGMP Signaling Pathway to Possible New Therapeutic Targets for Organelle Damage. [PDF]

J Inflamm Res
Wang W, Wang L, Lin H.
europepmc   +1 more source

Investigating the functional capacity of porcine uterine natural killer cells during a porcine reproductive and respiratory syndrome virus infection of pregnant gilts. [PDF]

Vet Res
Sawyer S, Stas MR, Lagumdzic E, Stadler M, Kreutzmann H, Knecht C, Dolezal M, Saalmüller A, Rümenapf T, Mair KH, Buzanich-Ladinig A.   +10 more
europepmc   +1 more source