Results 141 to 150 of about 8,307,083 (334)

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Inter-decadal variability of degree-day factors on Vestari Hagafellsjökull (Langjökull, Iceland) and the importance of threshold air temperatures [PDF]

The skill of degree-day glacier melt models is highly dependent on the choice of degree-day factor (DDF), which is often assumed to remain constant in time.
Hodgkins, R, Matthews, TR
core  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Vol. 11, No. 3, Mar. 18, 2005: Illinois Fruit and Vegetable News [PDF]

, 2005
published or submitted for publicationnot peer ...
Weinzierl, Rick
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Increasing the Reliability and Scope of NEWA Weather and Pest Model Information in the Lake Erie Region (Year 1 progress report) [PDF]

, 2017
NYS IPM Type: Project ReportObjectives: 1. Increase reliability of weather and pest model information provided through the NEWA website through monitoring and machine maintenance. 2. Increase adoption of the phenology-based degree-day model for timing of
Martin, Kevin, Weigle, Tim
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Assessing the role of fertility levels and biofertilizers on growing degree days, NDVI and chlorophyll in malt barley (Hordeum vulgare)

The Indian Journal of Agricultural Sciences
The experiment was conducted during 2020–2022 at Maharana Pratap University of Agriculture and Technology, Udaipur, Rajasthan to assess the impact of different fertility levels and biofertilizer treatments on malt barley (Hordeum vulgare L.).
SONAL ATHNERE, P C CHAPLOT, RAJENDRA PATEL, SURYAKANT NAGRE, KANGUJAM BOKADO, PINKY YADAV, SUNDAR ANCHRA   +6 more
doaj   +1 more source

Alfalfa Weevil Hatch is Upon Us [PDF]

, 2009
The map below indicates the accumulated degree days for each of the nine Iowa crop reporting districts. Degree-day information indicates that alfalfa weevil larvae should be hatching this week in southern Iowa. In central Iowa counties, weevils should be
Pope, Richard O., Tollefson, Jon J.
core   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source