Results 171 to 180 of about 14,831,698 (353)

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

A new growing degree-day phenology model for wheat stem sawfly (Hymenoptera: Cephidae) in Colorado wheat fields. [PDF]

open access: yesPLoS One
Vieira HV   +8 more
europepmc   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Improving the degree-day model for forecasting Locusta migratoria manilensis (Meyen) (Orthoptera: Acridoidea). [PDF]

open access: yesPLoS One, 2014
Tu X   +8 more
europepmc   +1 more source

Hobo Day Button, 1976

open access: yes, 1976
Hobo Day button - blue background, orange and white lettering - Weary Will walking, carrying a stick with a sack attached - text reads 'The American Dream, Hobo Day! Oct. 16, 1976, SDSU vs.
Hobo Day Committee (South Dakota State University)
core  

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy