Results 141 to 150 of about 1,551,640 (337)

The influence of zirconia veneer thickness on the degree of conversion of resin-matrix cements: an integrative review

open access: green, 2021
Christie M. Tafur-Zelada   +5 more
openalex   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Influence of Preheating Self-Adhesive Cements on the Degree of Conversion, Cell Migration, and Cell Viability

open access: yesApplied Mechanics
Enhancing the degree of polymerization can mitigate the cytotoxic effects of resinous materials, as residual monomers have been identified as a significant contributor to cytotoxicity.
Henrique Cantarelli   +7 more
doaj   +1 more source

Correlation between the degree of conversion and the elution of leachable components from dental resin-based cements [PDF]

open access: yesJournal of the Serbian Chemical Society, 2011
This study examined the possible correlation between the degree of conversion (DC) and the amount of substances eluted from three commercial cured resin-based cements.
KOSOVKA OBRADOVIĆ-DJURIČIĆ   +3 more
doaj  

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

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