Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Degree of conversion and microhardness of different composite resins polymerized with an advanced LED-curing unit. [PDF]
Ozciftci G, Boyacioglu H, Turkun LS.
europepmc +1 more source
Post-Cure Development of the Degree of Conversion and Mechanical Properties of Dual-Curing Resin Cements. [PDF]
Carek A +5 more
europepmc +1 more source
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Shrinkage, Degree of Conversion, Water Sorption and Solubility, and Mechanical Properties of Novel One-Shade Universal Composite. [PDF]
Ling L, Lai T, Chung PT, Malyala R.
europepmc +1 more source
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Dimensional accuracy and degree of conversion of a novel self-polymerized acrylic resin modified with chlorhexidine-halloysite nanotubes: An in vitro controlled study. [PDF]
Al Ansari N +4 more
europepmc +1 more source
Assessment of Micro-Hardness, Degree of Conversion, and Flexural Strength for Single-Shade Universal Resin Composites. [PDF]
Yılmaz Atalı P +9 more
europepmc +1 more source
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source

