Results 51 to 60 of about 167,616,501 (293)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Enzymatic Preparation of the Peptide of Cucumaria frondosa and Its Antioxidant Evaluation

Shipin gongye ke-ji, 2022
In this paper, peptide was prepared from Cucumaria frondosa by enzymatic hydrolysis with complex protease, and its composition and antioxidant capacities were evaluated.
Jinli LIU, Fang FAN, Xiaoxia HE, Shengcan ZOU, Tingfeng CAO   +4 more
doaj   +1 more source

Bitterness in sodium caseinate hydrolysates: role of enzyme preparation and degree of hydrolysis [PDF]

Journal of the Science of Food and Agriculture, 2017
AbstractBACKGROUNDEnzymatic hydrolysis of sodium caseinate (NaCas) may lead to the development of bitterness. Careful selection of hydrolysis conditions (i.e. enzyme preparation and duration) yielding different degrees of hydrolysis (DH) may aid in the development of low bitterness.RESULTSEighteen NaCas hydrolysates were generated with four enzyme ...
O'Sullivan, Dara, Nongonierma, Alice B., Fitzgerald, Richard J.   +2 more
openaire   +2 more sources

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

The complete mechanism of epoxyether hydrolysis [PDF]

, 1971
The hydrolysis of two epoxyethers, l-methoxy-2-ethyl-1,2-epoxybutone (MEE) and l-methoxy-l-phenyl-2-methyl-l,2-epoxybutane (MPME), has been studied in 10% (v/v) aqueous dioxane over the pH range 3-13 at 25°.
Mori, Arthur Laurance
core   +1 more source

Optimization of technological parameters of casein hydrolysis

Пищевые системы
Milk proteins are valuable raw materials for obtaining protein hydrolysates and active peptides formed during hydrolysis. Various proteolytic enzymes and bacteria are most often used for hydrolysis.
O. V. Zinina, I. M. Chanov, M. B. Rebezov, Y. Li, Ch. Li, Y. Zhao   +5 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Obtaining and estimating the potential of protein nutraceuticals from highly mineralized collagen-containing beef raw materials

Теория и практика переработки мяса, 2021
Highly mineralized collagen-containing beef raw materials (tibia, fibula and costal bones) are a source of valuable protein nutraceuticals. They include high molecular weight proteins, oligopeptides and amino acids, which anabolic and physiological ...
N. Yu. Mezenova, S. V. Agafonova, O. Ya. Mezenova, L. S. Baidalinova, T. Grimm   +4 more
doaj   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

The Effect of Enzyme, Time and Temperature on the Properties of Hydrolyzed Protein of Viscera Grass Carp (Ctenopharyngodon idella) [PDF]

Pizhūhish va Nuāvarī dar ̒Ulūm va Sanāyi̒-i Ghaz̠āyī, 2018
The purpose of this study was to investigate the effect of enzyme kind, time and temperature on the properties of viscera (Ctenopharyngodon idella) hydrolyzed proteins.
Atena Rafatinia, Laleh Roomiani
doaj   +1 more source