Results 121 to 130 of about 708,969 (305)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Fractional stochastic differential equations and degree theory: a unified perspective

Boundary Value Problems
This research focuses on the existence and uniqueness of solutions for a novel class of tempered φ-Caputo stochastic fractional differential equations.
M. Latha Maheswari, Karthik Muthusamy, E. Angeline Prashanthi   +2 more
doaj   +1 more source

Degree theory for 4-dimensional asymptotically conical gradient expanding solitons

, 2023
We develop a new degree theory for 4-dimensional, asymptotically conical gradient expanding solitons. Our theory implies the existence of gradient expanding solitons that are asymptotic to any given cone over $S^3$ with non-negative scalar curvature.
Bamler, Richard H., Chen, Eric
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Edge Degree Weight of Sequential Join of Graphs

Science Journal of University of Zakho, 2013
Let the weight w of an edge e= uv={u,v} of a graph G be defined by w(e)=deg(u)+deg(v)-2 and the weight of G be defined by w(G)= ∑ e ∈ E(G)w(e), where E(G) is the edge set of G.
Khidir R. Sharaf, Didar A. Ali
doaj  

Understanding Australian pharmacy degree holders’ job preferences through the lens of motivation-hygiene theory

Increasing the contribution of pharmacists to primary care has been long discussed, particularly in the context of health workforce shortages and the push to better integrate all providers across primary care.
Spinks, J, Freeman, C, Lancsar, E, Thai, T, Chen, G   +4 more
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Degree theory for the sum of VMO maps and maximal monotone maps

Cubo, 2011
Let be an open bounded domain, a VMO map, and T : D(T) a maximal monotone map wit . We construct a degree for the sum of f + T, which can be viewed as a generalization of the degree both for VMO maps and maximal monotone maps.Sea un dominio abierto, un ...
Yuqing Chen, Donal O'Regan, Ravi P Agarwal   +2 more
doaj  

Notes on low degree L-data

, 2017
These notes are an extended version of a talk given by the author at the conference Analytic Number Theory and Related Areas held at Research Institute for Mathematical Sciences, Kyoto University in November 2015.
Oliver, T.
core  

Infinite-dimensional degree theory and stochastic analysis

, 2010
The main aim of this paper is to describe how stochastic analysis is applied to infinite-dimensional degree theory for measurable maps of Banach spaces and Fredholm maps between Banach manifolds.
Elworthy, K. D., Al-Hussein, A., K. D. Elworthy, A. Al-Hussein   +3 more
core   +1 more source